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11#
發(fā)表于 2025-3-23 11:32:44 | 只看該作者
Clinical Applications of Drug Studiesain unanswered and many new ones continue to arise. Schizophrenia remains a poorly-understood group of disorders with considerable individual variations. Superimposed on these variations arc the many complex factors which govern drug response. To complicate matters further, it has recently been hypo
12#
發(fā)表于 2025-3-23 15:40:48 | 只看該作者
Tardive Dyskinesia: Management and New Treatmenthat occurs during or following prolonged neuroleptic drug treatment (Crane, 1973; Gerlach, 1979; Baldessarini et al., 1980; Casey and Gerlach, 1982). Though first identified in Europe (Schonecker, 1957; Sigwald et al., 1959), it was described in the English literature by Uhrbrand and Faurbye in 1960
13#
發(fā)表于 2025-3-23 19:00:22 | 只看該作者
New Clinical Concepts on Neuroleptic-Induced Supersensitivity Disorders: Tardive Dyskinesia and Supeugs appeared safe at the beginning, it was soon discovered that their long-term side effects were associated with the central nervous system. First, tardive dyskinesia (Shonecker, 1957; Faurbye et al., 1964) and then supersensitivity psychosis (Chouinard, Jones and Annable, 1978; Chouinard and Jones
14#
發(fā)表于 2025-3-24 01:45:41 | 只看該作者
The Implications of Cerebral Ventricular Size for Neuroleptic Therapy of Schizophrenias that neuroleptics were curative or specifically anti-schizophrenic have been tempered by adoption of more rigorous diagnostic and outcome measures and by increasing awareness of long-term toxicities. At the present time, the following conclusions about the therapeutic role of neuroleptic drugs see
15#
發(fā)表于 2025-3-24 03:55:41 | 只看該作者
Clinical Significance of Neuroleptic Plasma Levelsewed and found to be deficient. In this paper, the relationship between neuroleptic plasma levels and response is reviewed, and proposals are made for further research. This area was last reviewed three or four years ago and this paper is concerned with bringing the older reviews up to date (Curry,
16#
發(fā)表于 2025-3-24 09:46:27 | 只看該作者
The Clinical Utility of Plasma Neuroleptic Levelsg clinical use of these levels, it is important to ask how they can be interpreted. Do they correlate with clinical effects? Theoretically, there is little reason to expect a strong correlation. There are too many confounding factors separating a level in blood from neuroleptic action in brain. Has
17#
發(fā)表于 2025-3-24 13:49:13 | 只看該作者
Neuroregulators and Schizophrenia: A Look at the Dopamine and Endorphin Hypothesesnetworks, has proved to be particularly important for psychiatry by providing a framework for new conceptions of mental illness. The neurotransmitters and neuromodulators function in different ways (Barchas et al. 1978) yet it is clear that these materials may be directly involved in severe disorder
18#
發(fā)表于 2025-3-24 15:16:22 | 只看該作者
Colin Lever,Raphael Kaplan,Neil Burgessorder as well as an understanding of the pharmacokinetics (disposition, turnover, and metabolism of the drug in body compartments), pharmacodynamies (interaction of the drug with its specific site of action) and toxic effects of the agent. Knowledge of the exact etiopathology of the disorder is extr
19#
發(fā)表于 2025-3-24 22:55:42 | 只看該作者
https://doi.org/10.1007/978-1-4615-9594-63). The medical management of the depressed geriatric patient may be complicated by his inability to tolerate drug side effects, by other illnesses from which he may be suffering, or by adverse interactions between antidepressant medications and other medications frequently used in his age group. Th
20#
發(fā)表于 2025-3-25 00:33:56 | 只看該作者
Jianwei Liu,Lin Bai,Chunxiao Jiang,Wei Zhang, and separation anxiety/school phobia. It is surprising that antidepressants are claimed to be effective in such diverse conditions as these four. Nevertheless, there are significant numbers of clinical reports suggesting their efficacy for these disorders. In order to establish the utility of anti
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