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樓主
發(fā)表于 2025-3-21 17:40:49 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱(chēng)Guide to Targeted Therapies: Treatment Resistance in Lung Cancer
編輯Federico Cappuzzo
視頻videohttp://file.papertrans.cn/391/390911/390911.mp4
圖書(shū)封面Titlebook: ;
出版日期Book 2015
版次1
doihttps://doi.org/10.1007/978-3-319-20741-4
isbn_softcover978-3-319-20740-7
isbn_ebook978-3-319-20741-4
The information of publication is updating

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發(fā)表于 2025-3-21 23:46:00 | 只看該作者
https://doi.org/10.1007/978-3-8349-4015-5Systemic therapy for advanced non-small-cell lung cancer (NSCLC) depends upon tumor biology or tumor histology, with targeted agents preferentially used in individuals with a specific driver mutation and chemotherapy used for patients whose tumors do not harbor such mutations, or following failure of targeted therapy.
板凳
發(fā)表于 2025-3-22 02:23:57 | 只看該作者
地板
發(fā)表于 2025-3-22 04:57:18 | 只看該作者
Introduction,In 2015, once again, statistics confirm non-small-cell lung cancer (NSCLC) as the leading cause of cancer-related death worldwide (Figure?1.1), with a median survival that rarely exceeds 10–12 months in unselected patients with metastatic disease treated with conventional chemotherapy [1,2].
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發(fā)表于 2025-3-22 11:46:23 | 只看該作者
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發(fā)表于 2025-3-23 00:25:18 | 只看該作者
https://doi.org/10.1007/978-3-030-99732-8s approval was based on the results of a large phase III study that showed improved overall survival with the combination of bevacizumab, a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor (VEGF), plus carboplatin/paclitaxel chemotherapy versus chemotherapy alone [1].
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發(fā)表于 2025-3-23 03:03:21 | 只看該作者
Resistance to crizotinib and therapeutic options,y to crizotinib due to the emergence of acquired resistance. In addition, approximately 30% of patients do not respond to the therapy even in the presence of the target, anaplastic lymphoma kinase (ALK).
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發(fā)表于 2025-3-23 08:36:17 | 只看該作者
Resistance to anti-angiogenic drugs and therapeutic options,s approval was based on the results of a large phase III study that showed improved overall survival with the combination of bevacizumab, a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor (VEGF), plus carboplatin/paclitaxel chemotherapy versus chemotherapy alone [1].
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