Titlebook: GnRH Analogues in Cancer and Human Reproduction; Volume IV Precocious B. H. Vickery,B. Lunenfeld Book 1990 Kluwer Academic Publishers 1990

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Hoe heeft het zover kunnen komen?,se in the sensitivity of bone to the resorbing action of parathyroid hormone (PTH), 1,25-dihydroxy-vitamin D. or other bone-resorbing agents [2, 3], Higher values for calcium in serum and urinary excretion of calcium [4, 5] have been observed in postmenopausal women, supporting the theory of an incr

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Reversible Inhibition of Sexual Maturation in Male Rats: A Safety Evaluation for the Use of LHRH Aned by cyproterone acetate, but the results are not fully satisfactory because of adrenal steroid suppression and associated side effects. In girls, cyproterone acetate [1], danazol or medroxyprogesterone acetate [2] also have problems of side effects [3]. All steroids used for suppression of pituita

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Mechanism of Action of GnRH Analogues in Sexual Maturation and Function,secretion and in the control of sexual functions. The importance of the pulsatile nature of GnRH secretion for a physiologically meaningful stimulation of gonadotropin secretion has been recognized [1–4]. Many studies over the last decade have also confirmed the importance of GnRH secretion for the

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Should All Girls with Central Precocious Puberty be Treated by LHRH Analogue?,age progression which may lead to adult short stature. In girls, CPP presents with variable severity at first examination and, in some cases, spontaneous regression may even occur [1]. The impact on growth and bone maturation of mild forms of CPP is variable. This study was undertaken to better desc

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