Titlebook: Glycopeptides and Glycoproteins; Synthesis, Structure Valentin Wittmann Book 2007 Springer-Verlag Berlin Heidelberg 2007 Oligosaccharid.bio

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Chemical Synthesis of Glycopeptides,esisis particularly suited to provide uniform glycoprotein material, thus playing a?pivotal role for theadvancement of glycobiology. This chapter summarizes the recent progress achieved in glycopeptide synthesisincluding new glycosylation methods, enzymatic transformations, chemoselective ligation and recombinantexpression.

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https://doi.org/10.1007/978-3-642-50727-4ructures is essential for detailed determination of the role of glycosylation. Thisreview describes the use of enzymes for the synthesis of glycopeptides and glycoproteins, including theiruse as catalysts for glycosidic linkage formation and elaboration, peptide bond formation, and modification.

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Enzymatic Synthesis of Glycopeptides and Glycoproteins,ructures is essential for detailed determination of the role of glycosylation. Thisreview describes the use of enzymes for the synthesis of glycopeptides and glycoproteins, including theiruse as catalysts for glycosidic linkage formation and elaboration, peptide bond formation, and modification.

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Ph. Bamberger,R. Degkwitz,A. Wiskottogress in thefield of synthetic glycosylated amino acids, peptides, and proteins with non-natural structural elementswith a?focus on the carbohydrate–peptide linkage. Linear and convergent approaches are discussed.Application of chemoselective ligation reactions provides access to pure glycoforms of glycoprotein mimetics.

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Conformation of Glycopeptides and Glycoproteins,data, and dealing with molecules that show local or global disorder. We will provide an overviewof our knowledge of glycoprotein and glycopeptide structure, and illustrate with selected examples the performanceand limitations of current methodology.

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Glycopeptides and Glycoproteins978-3-540-36761-1Series ISSN 0340-1022 Series E-ISSN 1436-5049