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Titlebook: Glycoimmunology in Xenotransplantation; Cheorl-Ho Kim Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusive license t

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發(fā)表于 2025-3-21 17:22:38 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Glycoimmunology in Xenotransplantation
編輯Cheorl-Ho Kim
視頻videohttp://file.papertrans.cn/388/387090/387090.mp4
概述Covers the fundamental theories of autotransplantation, allotransplantation, and xenotransplantation.Delves into mammalian immune defense, protection from invaders, and blood coagulation.Highlights re
圖書(shū)封面Titlebook: Glycoimmunology in Xenotransplantation; Cheorl-Ho Kim Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusive license t
描述.This book describes general glycobiology in emphasizing the structures, biosynthesis, glycosylation and distribution of the glycans and xenogenic glycoantigens in eukaryotic cells of mammals including mouse, swine, chimpanzee and human. In the middle, I have focused on topics in xenotransplantation glycobiology and expand descriptions of allogenic and xenoantigenic transplantation to open the dawn in insights into the origin of life. One of the biological diversity, named species diversity, is a phenomenon environmentally adapted from the evolutionary process for long period. The distinct structures of glycans discriminate each organism and are the essential molecular basis of the discrimination and difference between the organisms, giving an incompatibility between the different species. Diversity and variations in carbohydrate chain structures between family, species, kingdoms and domains mark the global pattern and signs of immune self- and non-self recognition. In human, diversity in ABH blood group antigens is observed in human family and this type pattern distinguishes individuals from a pan-family to non-dividable unit of the family. Blood transfusion and organ transplantat
出版日期Book 2024
關(guān)鍵詞carbohydrate antigen; xenotransplantation; ER/Golgi apparatus; biological diversity; glycan-based Evolut
版次1
doihttps://doi.org/10.1007/978-981-99-7691-1
isbn_softcover978-981-99-7693-5
isbn_ebook978-981-99-7691-1
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
The information of publication is updating

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板凳
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Current State of Xenotransplantation,cally require organ donors, and the donor organs are incredibly limited in their number when compared to the demanders. In fact, there are about 40,000 people waiting for organ transplants in Korea; however, only about 200 organ donors are registered on the official site [data available from URL: .
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發(fā)表于 2025-3-23 00:57:06 | 只看該作者
Pig as Best Source for Clinical Xenotransplantation, mainly the organs rather than tissues and cells. As mentioned earlier, genetically edited and modified pig organs with multiple genes are attracted to solve the issues of donor organ supply and shortage. However, hurdles still include natural antibodies reactive to xenoantigens in human, and theref
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發(fā)表于 2025-3-23 04:31:23 | 只看該作者
Glycan Antigens of Pig Interfering with Xenotransplantation: Three Immune Responses from the Glycansmic reticulum (ER) and Golgi apparatus, the .-glycans not only stabilize the protein synthesis process in ER and Golgi apparatus but also relates to cell-to-cell communication in cell membranes. Furthermore, glycans are also important to immune responses due to their interaction with lectins. All a
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發(fā)表于 2025-3-23 06:45:15 | 只看該作者
Glycosylation in Eukaryotes,-specific expression patterns of the glycans are crucial for their fate determination of roles to the organisms. This specific phenomenon is a complicated event specific only for the eukaryotic cells and populations who have the small organelle of endoplasmic reticulum (ER) and Golgi apparatus. This
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