Titlebook: Genomic Instability and Cancer Metastasis; Mechanisms, Emerging Chris Maxwell,Cal Roskelley Book 2015 Springer International Publishing Swi

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https://doi.org/10.1007/978-3-319-12136-9Cancer Metastasis; DNA damage response; Genomic instability; Therapeutic approaches; Tumor heterogeneity

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Genomic Instability and Cancer Metastasis978-3-319-12136-9Series ISSN 1568-2102 Series E-ISSN 2215-1648

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Chris Maxwell,Cal RoskelleyConnects cancer metastasis with genomic instability in a comprehensive manner.Outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes.Reviews emerging themes and highl

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Gonorrhoische Erkrankungen der Haut,efect in DNA repair, and secondary cancers developed following treatment with chemotherapeutic drugs that damage the DNA. We will focus on four major repair pathways with particular attention to the exploitation of recent knowledge to improve cancer therapy.

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Microenvironmental Control of Metastatic Progression,ental alterations can have profound effects on the genome and epigenome of tumor cells as well as their signal transduction pathways, both biochemical and mechanical. All of these effects contribute to the invasion and progression of the metastatic tumor organ.

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