Titlebook: Genomic Imprinting; Jon F. Wilkins Book 2008 Springer-Verlag New York 2008 Allele.DNA.Promoter.genes.transcription

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Genomic Imprinting978-0-387-77576-0Series ISSN 0065-2598 Series E-ISSN 2214-8019

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Control of Imprinting at the , Cluster,had indicated regions of the genome that were likely to contain imprinted genes. Distal mouse chromosome 2 is one such region and is associated with devastating but ostensibly opposite phenotypes when exclusively maternally or paternally derived. Misexpression of proteins encoded at the . complex, w

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The , Locus and Pseudohypoparathyroidism,ociated with different forms of PHP involve the α-subunit of the stimulatory G protein (Gsα), a signaling protein essential for the actions of PTH and many other hormones. Heterozygous inactivating mutations within Gsα-encoding . exons are found in patients with PHP-Ia, who also show resistance to o

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