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Titlebook: Genome Instability; Methods and Protocol Marco Muzi-Falconi,Grant W Brown Book 2018 Springer Science+Business Media LLC 2018 eukaryotes.tel

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發(fā)表于 2025-3-21 16:33:48 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Genome Instability
副標(biāo)題Methods and Protocol
編輯Marco Muzi-Falconi,Grant W Brown
視頻videohttp://file.papertrans.cn/383/382843/382843.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia
叢書(shū)名稱Methods in Molecular Biology
圖書(shū)封面Titlebook: Genome Instability; Methods and Protocol Marco Muzi-Falconi,Grant W Brown Book 2018 Springer Science+Business Media LLC 2018 eukaryotes.tel
描述.This volume presents forty-two methods and protocols to analyze diverse aspects of genome instability. Chapters detail mutagenesis and repair, methods to quantify and analyze the properties of DNA double-strand breaks, profile replication, replication proteins strand-specifically, genome instability, fluorescence microscopic techniques, and genomic and proteomic approaches. Written in the highly successful?.Methods in Molecular Biology?.series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.. .Authoritative and cutting-edge,?.Genome Instability: Methods and Protocols.?aims to provide a comprehensive resource for the discovery and analysis of the proteins and pathways that are critical for stable maintenance of the genome..
出版日期Book 2018
關(guān)鍵詞eukaryotes; telomere maintenance; yeast; stem cell renewal; cancer biology
版次1
doihttps://doi.org/10.1007/978-1-4939-7306-4
isbn_softcover978-1-4939-8447-3
isbn_ebook978-1-4939-7306-4Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media LLC 2018
The information of publication is updating

書(shū)目名稱Genome Instability影響因子(影響力)




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Study of UV-induced DNA Repair Factor Recruitment: Kinetics and Dynamics, only a very small portion of the nucleus of a cell by letting UV light pass only through the pores. Immunofluorescent analyses of modified DNA nucleotides, proteins, or fluorescently tagged versions of target factors can be used as markers to label and study UV-induced lesions and their repair.
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,Revisiting “Sordid Fantasies”,addition, I provide tools for analyzing data from fluctuation assays. This 96-well plate protocol has been optimized for use in yeast but should perform equally well for a range of microorganisms using standard microbiological methods.
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,Measuring Mutation Rates Using the Luria-Delbrück Fluctuation Assay,addition, I provide tools for analyzing data from fluctuation assays. This 96-well plate protocol has been optimized for use in yeast but should perform equally well for a range of microorganisms using standard microbiological methods.
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Molecular Genetic Characterization of Mutagenesis Using a Highly Sensitive Single-Stranded DNA Repoof long stretches of single-stranded DNA in budding yeast cells. This system is ~100- to ~1000-fold more susceptible to mutation than conventional double-stranded DNA reporters, and is well suited for generating large mutational datasets to investigate the properties of mutagens.
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