Titlebook: Genome Editing in Cardiovascular and Metabolic Diseases; Junjie Xiao Book 2023 The Editor(s) (if applicable) and The Author(s), under excl

GIST

Conceptualizing Destructive Coordination, genetics involving an orchestrated series of genetic events and over 400 genes are responsible for myocardial development. Cooperation is required from a vast series of genetic networks, and mutations in such can lead to CHD and cardiovascular abnormalities, affecting up to 1% of all live births. G

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https://doi.org/10.1007/978-1-137-58880-7ing is a technology utilized to alter endogenous genes. Genome editing also provides an option to induce cardioprotective genes or inhibit genes linked to adverse cardiac remodeling and thus has promise in ameliorating DMCM. Non-coding genes have emerged as novel regulators of cellular signaling and

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E. Galán,R. Ca?ada,F. Fernández,B. CerveraENs), the recent breakthrough in the field has been related to clustered regularly interspaced short palindromic repeats/associated proteins (CRISPR/Cas). The high efficiency and convenience of CRIPSR/Cas systems dramatically accelerate pre- and clinical experimentations of dyslipidemia and atherosc

膽小懦夫

Mary Evans,Sarah Moore,Hazel Johnstonertality of patients with chronic diseases. At present, no effective clinical treatments for muscle atrophy except for exercise are available. The emerging field of genome editing is gaining momentum as it has shown great advantage in the treatment of various diseases, including muscle atrophy. In ou

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Kaisa M. Hartikainen,Robert T. Knightmost common causes of chronic liver disease worldwide among adults and children. It is characterized by excessive fat accumulation in the liver cells. It has a genetically heterogenous background with complex pathogenesis and progressions and is accompanied by significant morbidity, mortality, and h

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https://doi.org/10.1007/978-3-642-68387-9 in pathogenesis of diabetes and its complications. There are several established genes such as ABCC8, TCF7L2, SLC2A2, and CAPN10 which are known to influence blood insulin and glucose levels. Current management of diabetes types may include lifetime burdensome use of insulin, insulin sensitizers, i

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