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Titlebook: Genetic and Molecular Epidemiology of Multiple Myeloma; Suzanne Lentzsch Book 2013 Springer Science+Business Media New York 2013 IRESs.Kah

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發(fā)表于 2025-3-21 17:42:26 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Genetic and Molecular Epidemiology of Multiple Myeloma
編輯Suzanne Lentzsch
視頻videohttp://file.papertrans.cn/383/382664/382664.mp4
概述Explores the role of protein translation in multiple myeloma.Discusses epigenetic gene silencing as a new target for multiple myeloma immune surveillance.Examines the cell cycle control of plasma cell
圖書封面Titlebook: Genetic and Molecular Epidemiology of Multiple Myeloma;  Suzanne Lentzsch Book 2013 Springer Science+Business Media New York 2013 IRESs.Kah
描述Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cases of multiple myeloma arise from an asymptomatic monoclonal gammopathy of unknown significance. The exact mechanism of the transition from MGUS to overt multiple myeloma is still not well understood. Recent oncogenomic studies have further advanced our understanding of the molecular pathogenesis of multiple myeloma. This book will give a comprehensive overview of the genetic and molecular epidemiology of multiple myeloma in order to get a more refined and conclusive understanding of this disease.
出版日期Book 2013
關(guān)鍵詞IRESs; Kahler‘s disease; MGUS; bone disease; protein translation
版次1
doihttps://doi.org/10.1007/978-1-4614-4660-6
isbn_softcover978-1-4899-9865-1
isbn_ebook978-1-4614-4660-6
copyrightSpringer Science+Business Media New York 2013
The information of publication is updating

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發(fā)表于 2025-3-21 20:38:17 | 只看該作者
advanced our understanding of the molecular pathogenesis of multiple myeloma. This book will give a comprehensive overview of the genetic and molecular epidemiology of multiple myeloma in order to get a more refined and conclusive understanding of this disease.978-1-4899-9865-1978-1-4614-4660-6
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Gene Expression Signature in MGUS and Multiple Myeloma,
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IRES-Dependent, Cap-Independent Translation in Multiple Myeloma,
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Book 2013d approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cas
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發(fā)表于 2025-3-23 09:21:42 | 只看該作者
surveillance.Examines the cell cycle control of plasma cellMultiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple m
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