Titlebook: Genetic Counseling; Walter Fuhrmann,Friedrich Vogel Textbook 19833rd edition Springer-Verlag New York Inc. 1983 Chromosom.Erbkrankheit.Gen

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https://doi.org/10.1007/978-3-322-83071-5hromosomal changes. There is also a category whose genetic roots are best explained in terms of a multifactorial genetic system. Despite this, the entire chapter will be devoted to these diagnoses, and for two very specific reasons:

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https://doi.org/10.1007/978-1-4842-3243-9s of a particular mutagen is not always possible on the basis of direct observational data in man. However, the results of experimental mutation research with mammals give us additional evidence of the effects of particular mutagens (Hollaender, 1971, 1973; Vogel and R?hrborn, 1970; Vogel and Motulsky, 1979, Sect. 5.2).

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How Can Additional Information Be Incorporated into Genetic Risk Calculations?, information and advice to be presented during the actual counseling session. However, in some cases it is possible to derive further information from the pedigree, from the consideration of additional factors, and/or from supplementary tests that will permit a more accurate calculation of a specific risk.

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Prenatal Diagnosis of Genetic Abnormalities and Diseases,ecessary and useful to the physician in counseling his patients. Technical details are not discussed. The actual implementation of a prenatal diagnosis is a matter for specialized laboratories (for details see Milunsky, 1979; Murken et al., 1979; Galjaard, 1980; Hamerton and Simpson, 1980).

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