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Titlebook: Genes and Mechanisms in Vertebrate Sex Determination; Gerd Scherer,Michael Schmid Book 2001 Springer Basel AG 2001 Chromosom.Termination.V

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發(fā)表于 2025-3-21 19:54:35 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Genes and Mechanisms in Vertebrate Sex Determination
編輯Gerd Scherer,Michael Schmid
視頻videohttp://file.papertrans.cn/383/382409/382409.mp4
叢書名稱Experientia Supplementum
圖書封面Titlebook: Genes and Mechanisms in Vertebrate Sex Determination;  Gerd Scherer,Michael Schmid Book 2001 Springer Basel AG 2001 Chromosom.Termination.V
描述.Following an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions..
出版日期Book 2001
關(guān)鍵詞Chromosom; Termination; Vertebrate; chromosome; development; fish; genes; mammals; vertebrates; Model vertebr
版次1
doihttps://doi.org/10.1007/978-3-0348-7781-7
isbn_softcover978-3-0348-7783-1
isbn_ebook978-3-0348-7781-7Series ISSN 1664-431X Series E-ISSN 2504-3692
issn_series 1664-431X
copyrightSpringer Basel AG 2001
The information of publication is updating

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發(fā)表于 2025-3-21 20:42:34 | 只看該作者
Endocrine and environmental aspects of sex differentiation in gonochoristic fish,tiation in gonochoristic fish. The most important environmental determinant of sex would appear to be temperature. Interactions between environmental factors and genotype have been suggested for gonochoristic fish.
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https://doi.org/10.1007/978-3-030-58900-4t and sexual differentiation, this chapter reviews the studies that led to the isolation and characterization of WT1 and SF-1, and then discusses how interactions between these two genes may mediate their key roles in a common developmental pathway.
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https://doi.org/10.1007/978-94-011-1140-9opins and adrenal hormones but are sterile. .-deficient females are fertile. The DAX-1 protein, an unusual member of the nuclear hormone receptor, may act as a transcriptional repressor. It has been shown to both repress transcriptional activators by direct protein-protein interactions and to bind DNA hairpin structures and repress target genes.
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發(fā)表于 2025-3-23 08:20:45 | 只看該作者
Victoria Slettli,Xiang Ying Meil and genetic maps of the chicken genome. These efforts, in combination with modern molecular approaches to analyzing gene expression, should help to elucidate the sex-determining mechanism in birds in the near future.
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