Titlebook: General Methods in Biomarker Research and their Applications; Victor R. Preedy,Vinood B. Patel Reference work 2015 Springer Science+Busine

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Toxicogenomic and Pharmacogenomic Biomarkers for Drug Discovery and Personalized Medicine drug candidates at an early stage of drug development, resulting in a significant reduction in the time and cost associated with development of new molecular entities. A more detailed appreciation of the molecular mechanisms associated with a given toxicity potentially facilitates an enhanced abili

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Biomarkers in Urine and Use of Creatinine urinary biomarkers is evaluated, the fluctuation of urine volume (UV) should be corrected because the fluctuation causes the varied concentration of urinary biomarkers. Urinary biomarker excretion rate (UBER) corrected by UV itself is known as a gold standard method and is calculated as a product o

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Formalin-Fixed Paraffin-Embedded Tissue (FFPET) Sections for Nucleic Acid-Based Analysis in Biomarketion, because yield and quality of extracted nucleic acids are crucial for successful downstream applications. The described procedures usually achieve yields of several μg of high-quality RNA and DNA obtained from standard 5–10 μm FFPET sections; however, amounts significantly depend on factors lik

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Macrophage Inflammatory Protein-1 Alpha (MIP-1 alpha)/CCL3: As a Biomarkerter discusses the biological functions of MIP-1α/CCL3; describes several diseases associated with MIP-1α/CCL3, particularly periodontitis; and delineates the potential application of MIP-1α/CCL3 as a biomarker.

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Salivary Amylase as a Preoperative Marker of Anxiety in Perioperative Medicinel stimulus and changes in blood norepinephrine or heart rate variability indices strongly suggests that SA is an accurate marker of sympathetic nervous system activity. There is also an association between changes in SA during exposure to a stressful stimulus and changes in anxiety state. Saliva can

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Creatine as Biomarker syndromes. The measurement of Cr is used worldwide as the biomarker for the biochemical diagnosis of these diseases. Furthermore, numerous investigations have been carried out to analyze the relation between Cr and other metabolic pathways, such as the mitochondrial respiratory chain, the urea cycl

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