Titlebook: Gene and Cell Therapy: Biology and Applications; Giridhara R. Jayandharan Book 2018 Springer Nature Singapore Pte Ltd. 2018 gene therapy.c

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Rosanne B. McTyre,Linda M. Potternell as disadvantages which hinder their therapeutic endpoint in clinical trials. Now, researchers have made attempts to form virus encapsulated in chemical vectors which are called as hybrid vectors. These hybrid vectors have immense potential to evade host immune system by masking the immunogenic e

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https://doi.org/10.1007/978-3-030-36955-2 enhance and regulate a gene therapy or vice versa. Such combined approaches can hence increase the specificity and efficiency of the final therapy which may be much better than the individual ones. There are many hurdles to such dual-modality processes and hence must be employed after careful evalu

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Book 2018utics that rely on the delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles, and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) has had a tremendous impact on translational medicine. The chapters in this book cover a range o

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Adeno-associated Virus Vectors in Gene Therapystand factors that govern AAV infection in the host cell and the consequent cellular responses. This chapter will review this aspect of AAV-host cellular interactions and outline current developments in generating improved AAV vector systems for human gene therapy applications.

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