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Titlebook: Gene Therapy in Inflammatory Diseases; Christopher H. Evans,Paul D. Robbins Book 2000 Springer Basel AG 2000 Arthritis.DNA.apoptosis.carti

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發(fā)表于 2025-3-21 16:14:15 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱(chēng)Gene Therapy in Inflammatory Diseases
編輯Christopher H. Evans,Paul D. Robbins
視頻videohttp://file.papertrans.cn/382/381983/381983.mp4
叢書(shū)名稱(chēng)Progress in Inflammation Research
圖書(shū)封面Titlebook: Gene Therapy in Inflammatory Diseases;  Christopher H. Evans,Paul D. Robbins Book 2000 Springer Basel AG 2000 Arthritis.DNA.apoptosis.carti
描述Gene therapy for inflammatory diseases is a new , burgeoning field of medicine. Edited by the undisputed pioneers of this area of research, this volume is the first devoted to its topic. It contains thirteen chapters, each written by leaders in their respective fields, that summarize the state of the art in developing novel, gene based treatments for inflammatory diseases. As well as providing an introduction to the basic concepts of gene therapy and the use of naked DNA approaches, the book describes the advances that have been made in applying them to arthritis, lupus, multiple sclerosis, diabetes, Sjogren`s syndrome and transplantation.One chapter is devoted to discussing the first human clinical trials that apply gene therapy to the treatment of an inflammatory disease. As well as providing novel therapeutic approaches, gene therapy facilitates the development of new and improved animal models of disease; a chapter describing these advances is also included. As an up-to-date, timely book written by th
出版日期Book 2000
關(guān)鍵詞Arthritis; DNA; apoptosis; cartilage; clinical trial; cytokine; development; gene therapy; gene transfer; gen
版次1
doihttps://doi.org/10.1007/978-3-0348-8478-5
isbn_softcover978-3-0348-9584-2
isbn_ebook978-3-0348-8478-5Series ISSN 1422-7746 Series E-ISSN 2296-4525
issn_series 1422-7746
copyrightSpringer Basel AG 2000
The information of publication is updating

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Cartilage erosion in rheumatoid arthritis: studies in SCID mouse model,s. Although genetic factors have been frequently implicated in the pathogenesis of rheumatoid arthritis (RA) [1], and recent reports suggest mutations of tumor suppressor genes to play a role [2], RA is not caused by a specific genetic mutation. Much more likely it is an acquired disorder with a com
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Gene therapy for inflammatory diseases of the salivary glands, hypofunction. As salivary flow is compromised, patients experience oral dryness and difficulties with chewing, swallowing, and speaking. The absence of saliva is usually incompatible with normal oral health; diminished salivary flow results in mucosal inflammation, an increased incidence of oral in
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Gene therapy for management of lupus: Correction of Fas and Fas ligand-induced apoptosis in murine s of tolerance and autoimmune disease. Mutations of . and . are not a common cause of autoimmune disease in humans although a mutation of the . gene has been associated with autoimmune lymphoproliferative syndrome [1–5] and we have described a mutation of the . gene in one patient with systemic lupu
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Gene therapy for multiple sclerosis,allowing the scientific community to consider the treatment of these diseases using new modalities of immunotherapy. The classic forms of therapy for autoimmune disease are directed at general suppression of the immune response. In contrast, newer forms of therapy are aimed at specific cells or cyto
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發(fā)表于 2025-3-22 23:27:53 | 只看該作者
Gene therapy for type I diabetes mellitus,he insulin-producing β cells of the pancreatic islets of Langerhans. While evidence of a T lymphocyte involvement in the immunopathogenesis of the disease is demonstrated by histologic analysis of the pancreata from children at the onset of the disease and confirmed in animal models like the non-obe
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發(fā)表于 2025-3-23 06:58:14 | 只看該作者
DNA vaccination as an anti-inflammatory strategy,mmune responses is the key to their efficacy. There are two methods by which vaccines elicit immune responses. The first vaccines developed consisted of live attenuated pathogens which infect the host and stimulate a protective immune response. This includes the smallpox vaccine and the Sabin polio
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