Titlebook: Gene Engineering in Endocrinology; Margaret A. Shupnik Book 2000 Springer Science+Business Media New York 2000 Gonadotropin.glucocorticoid

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https://doi.org/10.1007/978-981-13-3047-6hypothalamic hormones growth hormone releasing factor (GRF) and somatostatin (SS). GRF exerts positive effects on GH secretion and synthesis and SS inhibits GH secretion. For review of the regulation of GH secretion see Hartman et al. .. In addition to GRF and SS, a synthetic peptide derived from en

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Anthony P. Mannarino,Judith A. Cohennsulin is underscored by the fact that the insulin receptor has been evolutionarily conserved and is found in organisms ranging from Drosophila to humans. Furthermore, insulin-dependent diabetes mellitus, a disease characterized by absolute insulin deficiency, was a uniformly fatal condition before

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The Environment and Child Development differentiation of cells and in oncogenic transformation .. At least 40 different Ets sequences have been identified in both vertebrates and invertebrates, representing approx 25 distinct proteins. The Ets gene family has not been detected in plants, fungi, or protozoans .. The founding member of t

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Anna Kaldal,Agnes Hellner,Titti Mattssonffects at the genomic level, although there are examples of nongenomic action in the cytoplasm, plasma membrane, and mitochondrion. Early observations clearly established that TH could bind to nuclear sites and stimulate transcription and translation of new proteins .. These important early observat

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Patrick J. McGrath,Susan Pistermanby high-affinity nuclear receptors coded on two genes termed TRα and TRβ . (Fig. 1). Each gene has multiple alternative mRNA splice products coding for isoforms with differential expression in development and in adult tissues. The syndrome of resistance to thyroid hormone (RTH) is the result of a de

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Children of International Migrants in Europe. Nuclear receptors are known to affect a wide array of important physiological effects in growth, development, and homeostasis and are key regulators of complex endocrine pathways. The field of reproductive endocrinology has been given a molecular boost by the discovery of two important members of

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