Titlebook: Gastrointestinal Oncology; Al B. Benson (Director) Book 1998 Springer Science+Business Media New York 1998 carcinoma.gastric cancer.geneti

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Molecular biology of pancreatic carcinoma,n cancer came within the last 20 years. Since the early discovery of oncogenic virus and cancer-causing mutagenic compounds, research has uncovered many families of genes that are, in some way, related to the tumorigenic pathway. The malignant phenotype represents the end result of not one genetic a

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0927-3042 treatment outcome. The incidence of new gastrointestinalcases recorded yearly for patients residing in the United States isapproximately 230,000, representing nearly 20% of all cancer cases.Worldwide, gastrointestinal malignancies are responsible for thelargest number of cancer deaths, particularly

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https://doi.org/10.1007/978-1-4614-1527-5ies directed at local control of the primary tumor become more palliative in nature, and any chance to significantly alter the natural history of the disease is predicated upon effective hepatic-directed therapy. The following chapter will provide an overview on surgical and nonsurgical hepatic-directed therapy for metastatic liver disease.

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Infection with Human Papillomavirus (HPV),motherapy with both FU plus levamisole and FU plus leucovorin has improved disease-free survival and survival in surgically resected stage III colon cancer. Analysis of the combined results of four previous NSABP trials also suggest the same relative benefit of adjuvant FU-based therapy for patients with node-negative colon cancer [1].

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