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Titlebook: Gasotransmitters in Organ Transplantation; A New Era in Transpl George J. Dugbartey Book 2024 The Editor(s) (if applicable) and The Author(

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發(fā)表于 2025-3-21 16:41:32 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱(chēng)Gasotransmitters in Organ Transplantation
副標(biāo)題A New Era in Transpl
編輯George J. Dugbartey
視頻videohttp://file.papertrans.cn/381/380811/380811.mp4
概述Provides the beneficial effects of gasotransmitters in organ transplantation.Presents a novel but simpler, safer and more cost-effective approach to organ preservation and transplantation.Discusses cl
圖書(shū)封面Titlebook: Gasotransmitters in Organ Transplantation; A New Era in Transpl George J. Dugbartey Book 2024 The Editor(s) (if applicable) and The Author(
描述.This book covers recent pre-clinical and clinical developments in gasotransmitters (nitric oxide, carbon monoxide and hydrogen sulfide) in all transplantable solid organs – kidney, heart, lung, liver, pancreas and intestine. Gasotransmitters are a class of small endogenously produced gaseous signaling molecules that play important roles in cellular homeostasis and impact physiological and pathophysiological situations. Recently, these gasotransmitters have emerged as potent cytoprotective mediators, possessing therapeutic properties that enable them exhibit their intracellular signaling functions. Hence, alterations in their physiological levels have been associated with various pathologies including cold ischemia-reperfusion injury (IRI) in organ transplantation. .In the context of organ transplantation, a novel therapeutic strategy that is being investigated involves administration of these gasotransmitters to the organ donor or recipient before or after transplantation, or supplementation of standard preservation solution with gasotransmitters during organ graft preservation to mitigate transplant-induced IRI. The book is divided into three parts for easier access: .Hydrogen Su
出版日期Book 2024
關(guān)鍵詞Organ transplantation; Gasotransmitters; ischemia-reperfusion injury; transplantable solid organs; Organ
版次1
doihttps://doi.org/10.1007/978-3-031-48067-6
isbn_softcover978-3-031-48069-0
isbn_ebook978-3-031-48067-6
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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O. Bartels,M. Neidhardt,H. Schellbergerplay important roles in cellular homeostasis and impact physiological and pathophysiological conditions. Nitric oxide was the first gasotransmitter to be identified followed by carbon monoxide, while hydrogen sulfide was recently established as the third member of the gasotransmitter family. Althoug
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https://doi.org/10.1007/978-3-031-52569-8llenge in solid organ transplantation (SOT), and represents a major factor that increases acute tubular necrosis, decreases graft survival, and delays graft function. This complicates graft quality, post-transplant patient care and organ transplantation outcomes, and therefore undermines the success
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https://doi.org/10.1007/978-3-7091-6384-9ong-term hemodialysis, optimal kidney preservation prior to transplantation remains a major challenge, as the gold standard of renal graft preservation by static cold storage tion in University of Wisconsin (UW) solution on ice at 4?°C contributes to graft injury and long-term post-transplantation c
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https://doi.org/10.1007/978-3-7091-0646-4opment of carbon monoxide-releasing molecules (CO-RM) and utilization of heme oxygenase-1 inducers have shown CO to be a promising therapy in reducing renal ischemia-reperfusion injury (IRI) and other inflammatory diseases. In this chapter, we will discuss the developments and application of CO-RM i
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