Titlebook: GABAB Receptor; Giancarlo Colombo Book 20161st edition Springer International Publishing Switzerland 2016 GABA B receptor.Gastroesophageal

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書目名稱GABAB Receptor影響因子(影響力)




書目名稱GABAB Receptor影響因子(影響力)學(xué)科排名




書目名稱GABAB Receptor網(wǎng)絡(luò)公開度




書目名稱GABAB Receptor網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱GABAB Receptor被引頻次




書目名稱GABAB Receptor被引頻次學(xué)科排名




書目名稱GABAB Receptor年度引用




書目名稱GABAB Receptor年度引用學(xué)科排名




書目名稱GABAB Receptor讀者反饋




書目名稱GABAB Receptor讀者反饋學(xué)科排名

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過濾

https://doi.org/10.1007/978-3-476-02825-9 of mesolimbic circuits. Beyond a physiological role GABA. receptors may also affect disease, such as addiction. GABA. receptors may therefore constitute an interesting target for pharmacological interventions to treat this condition.

勉強(qiáng)

https://doi.org/10.1007/978-3-476-04308-5t GABA. receptor agonists and positive allosteric modulators may have efficacy in the treatment of SUD, with GABA. receptor positive allosteric modulators having a better pharmacological profile than orthosteric agonists. There is the need for additional clinical studies to ascertain whether preclinical data translate to the human.

DEAWL

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The Allosteric Modulation of the GABAB Receptor: A Medicinal Chemistry Perspectivetural classes of GABA. allosteric modulators are described with an emphasis on structure–activity relationships (SAR) and synthesis of the main representatives of each class. Medicinal chemistry strategies to overcome issues related to allosteric modulators development are also discussed.

osculate

GABAB Receptor Functions in the Mesolimbic Dopamine System of mesolimbic circuits. Beyond a physiological role GABA. receptors may also affect disease, such as addiction. GABA. receptors may therefore constitute an interesting target for pharmacological interventions to treat this condition.

的闡明

Targeting the GABAB Receptor for the Treatment of Substance Use Disordert GABA. receptor agonists and positive allosteric modulators may have efficacy in the treatment of SUD, with GABA. receptor positive allosteric modulators having a better pharmacological profile than orthosteric agonists. There is the need for additional clinical studies to ascertain whether preclinical data translate to the human.

FELON

Targeting the GABAB Receptor for the Treatment of Alcohol Use DisorderA more recent avenue of research is represented by generalization of baclofen effects to the positive allosteric modulators of the GABA. receptor: preclinical data collected to date suggest that these compounds reproduce, with a much higher therapeutic index, several suppressing effects of baclofen on alcohol-motivated behaviors.

Grievance

1048-6909 nt perspectives from various fields of study including medic.An up-to-date comprehensive overview of the GABA B receptor system with a particular focus on the most recent therapeutic applications and potential. This receptor system has recently been implicated in several diseases and disorders inclu