| 書目名稱 | Fundamentals of Neurodegeneration and Protein Misfolding Disorders |
| 編輯 | Martin Beckerman |
| 視頻video | http://file.papertrans.cn/351/350416/350416.mp4 |
| 概述 | Presents a systematic, textbook-quality treatment of protein misfolding and its central role in neurodegeneration.Provides a foundation for understanding the multiple causes and progression of familia |
| 叢書名稱 | Biological and Medical Physics, Biomedical Engineering |
| 圖書封面 |  |
| 描述 | .This unique text introduces students and researchers to the world of misfolded proteins, toxic oligomers, and amyloid assemblages, and the diseases of the brain that result. During the past few years the connections between failures in protein quality control and neurological disorders have been reinforced and strengthened by discoveries on multiple fronts.?These findings provide novel insights on how amyloidogenic oligomers and fibrils form, interconvert from one state to another, and propagate from cell to cell and region to region. Starting with protein folding and protein quality control basics, the reader will learn how misfolded proteins can cause diseases ranging from prion diseases to Alzheimer’s disease and Parkinson’s disease to Huntington’s disease, amyotrophic lateral sclerosis and frontotemporal lobar degeneration. .Authoritative but?written in a clear and engaging style, .Fundamentals of Neurodegeneration and Protein Misfolding Disorders.?addresses one of today’s forefront areas of science and medicine. The text emphasizes the new groundbreaking biophysical and biochemical methods that enable molecular-level explorations and the conceptual breakthroughs that result. |
| 出版日期 | Textbook 2015 |
| 關(guān)鍵詞 | Abeta, Tau; Alpha-synuclein; Alpha-synucleinopathies; Alzheimer’s Disease; Amyloid Fibrils; Amyloid Oligo |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-22117-5 |
| isbn_softcover | 978-3-319-34284-9 |
| isbn_ebook | 978-3-319-22117-5Series ISSN 1618-7210 Series E-ISSN 2197-5647 |
| issn_series | 1618-7210 |
| copyright | Springer International Publishing Switzerland 2015 |
|Archiver|手機(jī)版|小黑屋|
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