| 書目名稱 | Frontiers in Protein Structure, Function, and Dynamics | | 編輯 | Dev Bukhsh Singh,Timir Tripathi | | 視頻video | http://file.papertrans.cn/350/349211/349211.mp4 | | 概述 | Presents methods to determine protein stability.Emphasizes the role of protein misfolding in neurodegenerative diseases.Reviews methods to determine three-dimensional structure of the protein and to u | | 圖書封面 |  | | 描述 | .This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances..Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecularmotors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins...?Overall, the book | | 出版日期 | Book 2020 | | 關(guān)鍵詞 | Protein function; Structural dynamics; Genetic variation; Enzyme inhibition; Post-Translational modifica | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-15-5530-5 | | isbn_softcover | 978-981-15-5532-9 | | isbn_ebook | 978-981-15-5530-5 | | copyright | Springer Nature Singapore Pte Ltd. 2020 |
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