Titlebook: Extracellular Matrix Omics; Sylvie Ricard-Blum Book 2020 Springer Nature Switzerland AG 2020 Extracellular matrix.Quantitative proteomics.

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Infection Control in the ICU Environmentpy a unique niche in biology. They have varied and essential roles as structural and regulatory molecules in numerous physiological processes and disease pathology. In regard to cellular context, some link the interior of the cell to the extracellular matrix (ECM) as transmembrane or membrane-anchor

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https://doi.org/10.1007/978-3-030-57317-1oteoglycans (PGs). GAGs and PGs play vital roles in?ECM-related processes such as cell migration, proliferation, adhesion, and differentiation. Among the . technologies, including genomics, transcriptomics, and proteomics, glycomics is the least mature. Over the past two decades, with efforts from g

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https://doi.org/10.1007/978-3-319-20669-1Ricard-Blum, Cold Spring Harb Perspect Biol 3:a004978, 2011), glycosaminoglycans (GAGs) and proteoglycans (PGs) (Iozzo and Schaefer, Matrix Biol 42:11–55, 2015; Karamanos et al., Chem Rev 118:9152–9232, 2018). We review here the major methods used to identify and characterize ECM protein, glycosamin

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Local Delivery of Antibiotic and Antiseptic and organs and to contain a vast pool of candidate biomarkers for a wide range of conditions. Thus, body fluids are regarded as highly attractive specimens for detecting disease disposition, to monitor markers of progression or to assess the efficacy of treatments. They provide several advantages f

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The Eye as a Model for Immune Privilege,ation, and migration. Cell-matrix interactions are mediated by integrin-associated adhesion complexes, multiprotein complexes of intracellular scaffolding and signalling proteins that link the cytoskeleton to the extracellular milieu. These linkages enable cells to sense and respond to the biochemic

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https://doi.org/10.1007/978-94-009-0077-6e variety of molecules including proteins, proteglycans and glycoaminoglycans. It contributes to cell signaling through the action of both its constituents and their proteolytic cleaved fragments called matricryptins. In addition, ECM acts as a “reservoir” of growth factors and cytokines and regulat

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978-3-030-58332-3Springer Nature Switzerland AG 2020

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Sylvie Ricard-BlumProvides a state-of-the art overview of extracellular matrix omics.Focuses especially on glycomics and glycobioinformatics.Elaborates on guiding principles for scientific data management