| 書目名稱 | Exploring Pancreatic Metabolism and Malignancy | | 編輯 | Ganji Purnachandra Nagaraju,Aramati BM Reddy | | 視頻video | http://file.papertrans.cn/320/319550/319550.mp4 | | 概述 | Highlights different metabolic diseases that are involved in the etiology and progression of pancreatic cancer.Describes the roles of inflammatory pathways in pancreatic cancer cell growth and metasta | | 圖書封面 |  | | 描述 | This book comprehensively describes the association between metabolic syndrome and pancreatic cancer progression, and the mechanism of action and target definition with a view to drug discovery. Metabolic syndrome, which includes adnominal obesity, hypertension, dyslipidemia, and hyperglycemia, has recently been shown to play an important role in the etiology and progression of various cancers. Further, obesity and diabetes have been associated with an?increased incidence of?gastric cancers. .The book reviews the key biological mechanisms underlying the association between metabolic dysregulation, including obesity-associated enhancement of growth factor signaling, inflammation, and perturbation in pancreatic cancer cell growth and metastasis. It also illustrates the role of the inflammatory signaling pathway in metabolic diseases as well as tumor growth and explores the potential of these pathways as the rational targets for pancreatic cancer therapy..Lastly, the bookoffers a comprehensive description of the challenges associated with diabetes and pancreatic cancer therapy. | | 出版日期 | Book 2019 | | 關(guān)鍵詞 | Metabolic syndrome; Diabetes; Pancreatic Cancer; Inflammation; Targeting molecules; metabolic disease | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-32-9393-9 | | isbn_softcover | 978-981-32-9395-3 | | isbn_ebook | 978-981-32-9393-9 | | copyright | Springer Nature Singapore Pte Ltd. 2019 |
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