Titlebook: Experimental Neurochemistry; Abel Lajtha Book 1982 Springer Science+Business Media New York 1982 CNS.Nervous System.PET.brain.cell.enzyme.

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Cell Isolation,d PNS, respectively) became possible after the development of photographic techniques and of the process of precipitation of silver salts in nervous structures.. By this technique, details of nerve fibers and shapes of neurons were revealed. On this basis, the neuron doctrine was formulated, i.e., t

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Principles of Compartmentation,les come readily to mind and include protein synthesis, the urea cycle, and the metabolism of glutamic acid. Typically, all cycles require a number of precisely sequenced metabolic steps which are not incorporated into a single anatomic entity. Therefore, any substance not immediately broken down by

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Perfusion of the Isolated Brain,r organelles and . techniques employing the intact animal. Although a considerable amount of useful information has been obtained from studies with these . and . systems, a number of difficulties are inherent in such preparations. For example, the usual membrane barriers are disrupted during prepara

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Mass Spectrometric Analysis of Some Neurotransmitters and Their Precursors and Metabolites,r precursors and metabolites in a variety of nervous and other tissues and in complex body fluids such as urine, cerebrospinal fluid (CSF), whole blood, and plasma. It is a very sensitive and relatively specific procedure and frequently is used in conjunction with a suitable separative method such a

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Gas Chromatography,emistry. In this chapter, we discuss one of the analytical tools in wide use, gas chromatography (GC). The purpose of this brief discussion of the principles involved and the use of selected examples of how the GC has been employed in analysis of endogenous components of the nervous system and in an