Titlebook: Experimental Design and Reproducibility in Preclinical Animal Studies ; José M. Sánchez Morgado,Aurora Br?nstad Book 2021 Springer Nature

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書目名稱Experimental Design and Reproducibility in Preclinical Animal Studies 讀者反饋學(xué)科排名

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Microbiology and Microbiomecrobiota. The animal host contains approximately 20,000 genes, while the microbiota contains more than 1?million genes. Therefore, many of the competences of a laboratory animal have arisen from the microbiota rather than the mammal genome. As there is substantial variation in composition between an

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Effects of Untreated Pain, Anesthesia, and Analgesia in Animal Experimentationory nervous system’s response to (potentially) harmful stimuli, but has been defined as a “subjective, sensory and emotional experience” [1, 2] in humans. It is very likely that pain, as an affective experience, also exists in other vertebrate animals than humans. Therefore, anesthesia and pain trea

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Why Do We Need a Statistical Experiment Design? stage where human trials can begin. We have to strike a harm/benefit balance, and these are now enshrined in the 3R’s principles of the European directive 2010/63/EU which is enacted in the laws of European countries. Good experimental design which will allow us to achieve this is therefore not onl

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Scholarly Publishing and Scientific Reproducibilityes. Improved author compliance to a journal’s submission guidelines, rigorous editorial vigilance by competent reviewers and journal editors, and revamped research practices and policies by research institutes can raise the reporting quality of submitted manuscripts. In this chapter, we describe the

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Defined Mutants in Higher Plants for example, states that “member states shall ensure that, unless it is inappropriate, procedures are carried out under general or local anesthesia, and that analgesia or another appropriate method is used to ensure that pain, suffering and distress are kept to a minimum.”