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Titlebook: Excitatory Amino Acids and Epilepsy; Robert Schwarcz,Yehezkel Ben-Ari Book 1986 The Editor(s) (if applicable) and The Author(s), under exc

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發(fā)表于 2025-3-21 17:50:23 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Excitatory Amino Acids and Epilepsy
編輯Robert Schwarcz,Yehezkel Ben-Ari
視頻videohttp://file.papertrans.cn/319/318394/318394.mp4
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Excitatory Amino Acids and Epilepsy;  Robert Schwarcz,Yehezkel Ben-Ari Book 1986 The Editor(s) (if applicable) and The Author(s), under exc
描述Human epilepsy is a major public health problem affecting approximately 2 persons per 1000. It is particularly frequent in ohildren where convul- sions may lead to brain damage and subsequent seizure activity in adulthood. Temporal lobe epilepsy (synonyms include limbic epilepsy. psychomotor epilepsy and complex partial epilepsy) is the most devastating form of epilepsy in the adult population since: a) it is often extremely resistant to currently available anticonvulsant drugs (i.e ?? it is more resistant than tonico-clonic or grand mal seizures) and b) it includes loss of consciousness. thereby limiting performance of many normal functions and leaving the individual susceptible to bodily injury. It is also associated with nerve cell loss. in particular in the hippocampus and other structures of the temporal lobes. In order to promote an appropriate therapy it is essential to understand the etiology of seizures and its relationship to brain damage. Basic research on epilepsy also provides a very useful vehicle to learn about the way the brain functions under normal conditions. For instance. much of our present understanding of the mechanisms of action of GABA and benzo- diazepines
出版日期Book 1986
關鍵詞Aspartat; Glutamat; amino acid; brain; cell; etiology; lead; population; protein; receptor; structure; synthesi
版次1
doihttps://doi.org/10.1007/978-1-4684-7971-3
isbn_softcover978-1-4684-7973-7
isbn_ebook978-1-4684-7971-3Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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Subcortical Projections from the Amygdaloid Complexeviously thought. For example, the central amygdaloid nucleus projects not only to the lateral hypothalamus, but also to the full extent of the brainstem and even into the spinal cord (e.g., Hopkins, 1975; Price and Amaral, 1981; Mizuno et al., 1985). At the other end of the neuraxis, the amygdaloid
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Cortical and Subcortical Afferents of the Amygdaloid Complexs from subcortical areas in the hypothalamus and brainstem, known to be of importance for drive and motivation. At the 1971 symposium on the neurobiology of the amygdaloid complex, Lammers (1972) reviewed the then known sources of afferents to the amygdala. These included the olfactory bulb, the pri
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Electrophysiology of Epileptic Tissue: What Pathologies are Epileptogenic?estrum et al., 1964; Heinemann et al., 1977; Woodbury and Kemp, 1977; French and Siggins, 1980; Schwartzkroin and Wyler, 1980; Lux and Heinemann, 1982; Ribak et al., 1982;. Dudek et al., 1983; Grisar et al., 1983; Scheibel et al., 1983; Schwartzkroin, 1983; DeLorenzo, 1984; Johnston and Brown, 1984;
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Blood-Brain Barrier Permeability to Excitatory Amino Acidsa specific carrier mechanism. These specific carriers are not all symmetrically distributed on the two membranes. Carriers on the luminal membrane seem to function mainly as exchange systems, while some carriers on the antiluminal membrane can produce active transport (Goldstein and Betz, 1983). An
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