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Titlebook: Excitatory Amino Acids; From Genes to Therap P. H. Seeburg,I. Bresink,L. Turski Conference proceedings 1998 Springer-Verlag Berlin Heidelbe

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11#
發(fā)表于 2025-3-23 10:47:39 | 只看該作者
Localisation and Surface Expression of the AMPA Receptor Subunit GluR1 Using Green Fluorescent Protrum 1994; Fletcher and Lodge 1996). In general, glutamate receptors can be characterised into two broad groups: (1) The ionotropic glutamate receptors (GluRs) which contain an integral ion channel, and (2) the metabotropic glutamate receptors (mGluRs) which are G-protein coupled.
12#
發(fā)表于 2025-3-23 14:20:12 | 只看該作者
https://doi.org/10.1007/978-3-662-03596-2Glutamat; Molekulargenetik in der Neurologie; Neurobiologie; Neurodegenerative Krankheiten; RNA; antibody
13#
發(fā)表于 2025-3-23 20:12:41 | 只看該作者
Von Computern, Netzen und fetten FischenIonotropic glutamate receptor (GluR) channels are assembled from structurally homologous subunits that can be grouped into three families according to sequence identity and agonist binding characteristics.
14#
發(fā)表于 2025-3-23 23:05:37 | 只看該作者
Calcium Permeability of Glutamate-Gated Channels in the CNS: Functional Role of the Ca2+-Permeable Ionotropic glutamate receptor (GluR) channels are assembled from structurally homologous subunits that can be grouped into three families according to sequence identity and agonist binding characteristics.
15#
發(fā)表于 2025-3-24 05:52:14 | 只看該作者
https://doi.org/10.1007/978-3-642-90766-1ate and NMDA receptor families (Collingridge and Lester 1989; Mayer and Westbrook 1987; Watkins et al. 1990). The AMPA receptors mediate the fast component of excitatory postsynaptic currents, whereas the slow component is contributed by NMDA receptors (e.g., Stern et al. 1992). The latter can be vi
16#
發(fā)表于 2025-3-24 08:03:59 | 只看該作者
Formeln und Tabellen der W?rmetechniks such as synaptogenesis, formation of neuronal circuitry, and synaptic plasticity, including long-term potentiation and long-term depression. However, excessive activation of GluRs contributes to neurodegeneration following a wide range of neurological insults including ischemia, trauma, hypoglycem
17#
發(fā)表于 2025-3-24 11:34:04 | 只看該作者
18#
發(fā)表于 2025-3-24 18:23:28 | 只看該作者
Formen ambulanter Gruppentherapiely selective for upper motor neurones, a proportion of which are represented by Betz cells (Fig. lA) in the fifth layer of the motor cortex, and for lower motor neurones in the ventral horn of the spinal cord (Fig. 1B) and brainstem. The selective vulnerability of motor neurones in ALS is relative a
19#
發(fā)表于 2025-3-24 21:25:05 | 只看該作者
20#
發(fā)表于 2025-3-25 02:13:23 | 只看該作者
,Kritische Würdigung der Arbeit,5-methyl-4-isoxazolepropionate (AMPA) and kainate (KA) receptor stimulation triggers Na+ influx into neurons, while N-methyl-D-aspartate (NMDA) receptor stimulation additionally leads to considerable Ca. influx (Hollmann and Heinemann 1994). Relative impermeability of the AMPA receptor channel to Ca
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