Titlebook: Evolutionary Genomics; Statistical and Comp Maria Anisimova Book‘‘‘‘‘‘‘‘ 2019Latest edition The Editor(s) (if applicable) and The Author(s)

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Selection Acting on Genomesnlarged our understanding of the genome evolution of various species. In this chapter, we will focus on methods to detect selection on the genome. In particular, we will discuss probabilistic models and how they have changed with the advent of new genome-wide data now available.

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Evolution of Viral Genomes: Interplay Between Selection, Recombination, and Other Forcesct in viruses, and, of course, viruses have clear biomedical relevance. Recent commoditization of affordable high-throughput sequencing has made it possible to generate truly massive genomic data sets, on which powerful and accurate methods can yield a very detailed depiction of when, where, and (so

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Evolution of Protein Domain Architecturesevolution and how these have been inferred from distributions of extant domain arrangements. Following this, we review inferences of ancestral domain architecture and the conclusions concerning domain architecture evolution mechanisms that can be drawn from these. Finally, we examine whether all kno

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