Titlebook: Esophageal Adenocarcinoma; Methods and Protocol Alfred K. Lam Book 2018 Springer Science+Business Media, LLC 2018 Esophagus.Carcinoma.Tumor

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Target Therapy for Esophageal Adenocarcinoma,eed to personalize treatment by identifying molecular targets and respective target therapy in esophageal adenocarcinoma. There has been success in targeting the human epidermal growth factor receptor 2 (HER2) and vasoendothelial growth factor (VEGF) pathway while more failures were encountered in t

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Histopathological Assessment for Esophageal Adenocarcinoma,tic carcinoma, adenosquamous carcinoma, and mucoepidermoid carcinoma. For adenocarcinoma, it is important to determine the grading of the cancer and histological variants such as signet ring adenocarcinoma. In the current day management of esophageal adenocarcinoma by neoadjuvant therapy, the histol

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Macroscopic Assessment and Cut Up of Endoscopic Resection Specimens for Early Esophageal Glandular agement. Proper macroscopic assessment and cut-up technique is essential to ensure that the overall assessment is correct and reproducible. Endoscopic mucosal resection is a technique used for removing early neoplastic glandular lesions of the esophagus at the level of submucosa. Here, we describe t

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Application of Pathological Staging in Esophageal Adenocarcinoma, includes parameters—extent of tumor (T), lymph node status (N), presence of distant metastasis (M), and grade of the adenocarcinoma (G). In addition, different criteria are used in patients with and without neoadjuvant therapy. The silent aspects of the use of new staging protocol are discussed.

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Application of Tissue Microarray in Esophageal Adenocarcinoma, It allows faster analysis and considerably reducing costs incurred in staining. The technique also provides a high-throughput analysis of multiple tissues for the different types of research. In the literature, many researches of esophageal adenocarcinoma use tissue microarray to enhance the output

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Predictive Marker: HER2 in Esophageal Adenocarcinoma,ssion of the protein products. Arising from that a “HER2-positive cancer” is one that shows . gene amplification and resultant protein expression as demonstrated by in situ hybridization and immunohistochemistry, respectively. Testing of the HER2 status is crucial to ensure selection of the correct

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Whole-Slide Imaging for Esophageal Adenocarcinoma,tion, and image analysis. In this process, a scanning equipment (scanner) scans the whole glass slide into a digital file. In research in esophageal adenocarcinoma or other cancers, whole-slide imaging could help in production of high-resolution images for studying and sharing of research informatio

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Animal Model: Reflux Models in Esophageal Adenocarcinoma,ERD)–Barrett’s esophagus–esophageal adenocarcinoma progression. Surgical reflux models in mice are technically challenging due to the small size and intolerance to surgical stress of mice. Herein, we detail three representative surgical procedures that allow for creation of an esophageal adenocarcin

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