| 書目名稱 | Epigenetics of Aging | | 編輯 | Trygve O. Tollefsbol | | 視頻video | http://file.papertrans.cn/314/313246/313246.mp4 | | 概述 | Intended for those with interests ranging from the fundamental basis of aging to interventions in slowing the aging process or treating age-related diseases.The study of epigenetics as it relates to a | | 圖書封面 |  | | 描述 | .Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research...The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an imp | | 出版日期 | Book 2010 | | 關鍵詞 | Chromosom; DNA; Telomere; aging; genetics; senescence | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4419-0639-7 | | isbn_softcover | 978-1-4899-8310-7 | | isbn_ebook | 978-1-4419-0639-7 | | copyright | Springer-Verlag New York 2010 |
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