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Titlebook: Epigenetics and Proteomics of Leukemia; A Synergy of Experim Rˉuta Navakauskien˙e,Dalius Navakauskas,Dalius Mat Book 2021 Springer Nature S

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書目名稱Epigenetics and Proteomics of Leukemia
副標(biāo)題A Synergy of Experim
編輯Rˉuta Navakauskien˙e,Dalius Navakauskas,Dalius Mat
視頻videohttp://file.papertrans.cn/314/313240/313240.mp4
概述Compiles the latest research on the study of epigenetics and proteomics of leukemia.Introduces computational methods to evaluate and analyze changes in proteome and chromatin remodeling.Demonstrates s
圖書封面Titlebook: Epigenetics and Proteomics of Leukemia; A Synergy of Experim Rˉuta Navakauskien˙e,Dalius Navakauskas,Dalius Mat Book 2021 Springer Nature S
描述.This book reviews the current state of epigenetics and proteomics of leukemia and introduces the methods that are important to process and evaluate these factors in leukemia. In particular, epigenetic modifiers and their inhibitors in leukemia treatment as well as approaches to the epigenetic treatment of leukemia are covered. Various computational methods for proteome analysis are also described in detail, including 2DE fractionation and visualization, proteomic data processing, image acquisition and data anlaysis, and more. Protein localization in leukemia is also covered, in addition to the future of leukemia therapy...Epigenetics and Proteomics of Leukemia?.is an ideal book for advanced biomedical scientists and students, medical doctors and students, bioinformatics and health informatics researchers, computational biologists, structural biologists, systems biologists, and bioengineers..
出版日期Book 2021
關(guān)鍵詞Epigenetics; Proteomics; Leukemia; Chromatin; 2DE; Protein Visualization; Computational Biology
版次1
doihttps://doi.org/10.1007/978-3-030-68708-3
isbn_softcover978-3-030-68710-6
isbn_ebook978-3-030-68708-3
copyrightSpringer Nature Switzerland AG 2021
The information of publication is updating

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Chromatin Remodeling During Leukemia Cell Proliferation and Differentiationion, transcription, and translation depend on chromatin structure. Therefore modifications of DNA and nuclear proteins—histones—play a key role in these processes and consequently in cell functioning and regulation. Chapter 3 represents effects of a large scale of DNMTi, HMTi and HDACi alone in vari
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Protein Translocation into the Nucleus during Leukemia Cell Differentiationcleus. In the Chap. 7 we have described a method for the study of protein translocation from the cytoplasm into the nucleus. And we provided a method for estimating where protein phosphorylation occurs. The identified tyrosine phosphorylated proteins translocated into the nucleus of leukemic cells d
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Protein Visualization in Leukemia Cells progression. Therefore, epigenetic modifiers used in cancer therapy have an impact to remodel chromatin with replacement of histone modifications and thus restore the normal state of cells. In Chap. 8 we demonstrated the comparative analysis of histones, their variants and modifications during gran
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Computational Methods for Protein Localization Analysisl) high-resolution fluorescence image acquisition generates a large amount of complex image data, and manual analysis of such data in order to distill biologically meaningful information is challenging. Automated image analysis is an inevitable approach to perform quantification of phenotypic change
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Book 2002gmentation results but also during the initial tuning of various parameters of the segmentation algorithm. Setting free from the tuning of initial parameters allows for faster switching to data analysis of the new experiment when imaging settings or other conditions were changed. The development of
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