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Titlebook: Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases; Barbara Stefanska,David J. MacEwan Book 2017 The Editor(s) (i

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https://doi.org/10.1007/978-1-4939-6743-8DNA methylation; Histone covalent modifications; Non-coding RNA mechanisms; Epigenomics; Nucleosome posi
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https://doi.org/10.1007/978-3-030-45435-7rome-associated mutations in genes encoding key enzymes of intermediary metabolism. Here, we provide an outline for the synthesis of cell-permeable forms of the cellular metabolites (.)-2-hydroxyglutarate and (.)-2-hydroxyglutarate, and their application for the inhibition of α-ketoglutarate-dependent Jumonji histone demethylases.
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Synthesis and Application of Cell-Permeable Metabolites for Modulating Chromatin Modifications Regurome-associated mutations in genes encoding key enzymes of intermediary metabolism. Here, we provide an outline for the synthesis of cell-permeable forms of the cellular metabolites (.)-2-hydroxyglutarate and (.)-2-hydroxyglutarate, and their application for the inhibition of α-ketoglutarate-dependent Jumonji histone demethylases.
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High-Throughput Screening of Small Molecule Transcriptional Regulators in Embryonic Stem Cells Usinr transcriptional regulators without well-defined functions, or as a secondary screen validating results obtained using a traditional reporter cell line or biochemical readout. Additionally, we provide useful guidelines and protocols for culturing and plating mouse embryonic stem (ES) cells for high
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