找回密碼
 To register

QQ登錄

只需一步,快速開始

掃一掃,訪問微社區(qū)

打印 上一主題 下一主題

Titlebook: Epigenetics and Disease; Pharmaceutical Oppor Susan M. Gasser,En Li Book 2011 Springer Basel AG 2011 DNA methylation.cancer.neuronal disord

[復(fù)制鏈接]
查看: 31557|回復(fù): 51
樓主
發(fā)表于 2025-3-21 18:08:47 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Epigenetics and Disease
副標(biāo)題Pharmaceutical Oppor
編輯Susan M. Gasser,En Li
視頻videohttp://file.papertrans.cn/314/313235/313235.mp4
概述Discusses new approaches to pharmaceutical intervention.Includes new findings from stem cell research.With numerous illustrations.Includes supplementary material:
叢書名稱Progress in Drug Research
圖書封面Titlebook: Epigenetics and Disease; Pharmaceutical Oppor Susan M. Gasser,En Li Book 2011 Springer Basel AG 2011 DNA methylation.cancer.neuronal disord
描述Epigenetics has emerged recently as an important area of molecular biological studies. Epigenetic modifications lead to potentially heritable but reversible alterations in the expression of genes that determine cell fate. Epigenetic misregulation is thus often linked to degenerative diseases, cancer and neuronal disorders.Recent biomedical interest in this regulatory system stems from the fact that epigenetic, in contrast to genetic, alterations are in principle amenable to pharmacological intervention. A few epigenetically active drugs, for example histone deacetylase inhibitors (HDACi) and DNA methyltransferase (DNMT) inhibitors, have been approved by FDA for treatment of cancers such as CTCL, MDS, and AML.This volume explores the scientific background for clinical applications of epigenetically active drugs.Included are descriptions of epigenetic controls over gene expression, the post-transcriptional silencing of genes by RNA interference (RNAi) and microRNAs, as well as new findings from stem cell research which are relevant to pharmacological applications.
出版日期Book 2011
關(guān)鍵詞DNA methylation; cancer; neuronal disorders; stem cells; therapy
版次1
doihttps://doi.org/10.1007/978-3-7643-8989-5
isbn_softcover978-3-0348-0305-2
isbn_ebook978-3-7643-8989-5Series ISSN 0071-786X Series E-ISSN 2297-4555
issn_series 0071-786X
copyrightSpringer Basel AG 2011
The information of publication is updating

書目名稱Epigenetics and Disease影響因子(影響力)




書目名稱Epigenetics and Disease影響因子(影響力)學(xué)科排名




書目名稱Epigenetics and Disease網(wǎng)絡(luò)公開度




書目名稱Epigenetics and Disease網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱Epigenetics and Disease被引頻次




書目名稱Epigenetics and Disease被引頻次學(xué)科排名




書目名稱Epigenetics and Disease年度引用




書目名稱Epigenetics and Disease年度引用學(xué)科排名




書目名稱Epigenetics and Disease讀者反饋




書目名稱Epigenetics and Disease讀者反饋學(xué)科排名




單選投票, 共有 0 人參與投票
 

0票 0%

Perfect with Aesthetics

 

0票 0%

Better Implies Difficulty

 

0票 0%

Good and Satisfactory

 

0票 0%

Adverse Performance

 

0票 0%

Disdainful Garbage

您所在的用戶組沒有投票權(quán)限
沙發(fā)
發(fā)表于 2025-3-21 22:17:31 | 只看該作者
America, Pakistan, and the India Factorysine demethylases (erasers). Importantly, epigenetic modifications impact chromatin structure directly or can be read by effector regulatory modules. Here, we summarize current knowledge on structural and functional properties of various histone lysine methyltransfereases and demethylases, with emphasis on their importance as druggable targets.
板凳
發(fā)表于 2025-3-22 03:53:02 | 只看該作者
https://doi.org/10.1007/978-94-6209-878-7ed in important human diseases, including cancer and hepatitis C. We discuss antisense strategies targeting miR-122 as a potential therapeutic approach to treat hepatitis C and possibly other diseases.
地板
發(fā)表于 2025-3-22 07:44:13 | 只看該作者
5#
發(fā)表于 2025-3-22 10:25:02 | 只看該作者
6#
發(fā)表于 2025-3-22 15:49:43 | 只看該作者
The Liver-Specific MicroRNA miR-122: Biology and Therapeutic Potential,ed in important human diseases, including cancer and hepatitis C. We discuss antisense strategies targeting miR-122 as a potential therapeutic approach to treat hepatitis C and possibly other diseases.
7#
發(fā)表于 2025-3-22 19:40:40 | 只看該作者
Small Molecules in Cellular Reprogramming and Differentiation,tions, but also such small molecules could be further developed as conventional therapeutics to target patient’s own cells residing in different tissues/organs for treating degenerative diseases, injuries, and cancer. Here, we will review recent studies of small molecules in controlling cell fate.
8#
發(fā)表于 2025-3-22 21:43:53 | 只看該作者
9#
發(fā)表于 2025-3-23 01:48:40 | 只看該作者
https://doi.org/10.1057/9781137432841 of epigenetic regulators, highlighting a potentially new avenue for therapeutic intervention. In this review, we discuss recent studies on epigenetic regulation in MR and explore the concept of epigenetic therapy for MR.
10#
發(fā)表于 2025-3-23 05:58:32 | 只看該作者
 關(guān)于派博傳思  派博傳思旗下網(wǎng)站  友情鏈接
派博傳思介紹 公司地理位置 論文服務(wù)流程 影響因子官網(wǎng) 吾愛論文網(wǎng) 大講堂 北京大學(xué) Oxford Uni. Harvard Uni.
發(fā)展歷史沿革 期刊點(diǎn)評(píng) 投稿經(jīng)驗(yàn)總結(jié) SCIENCEGARD IMPACTFACTOR 派博系數(shù) 清華大學(xué) Yale Uni. Stanford Uni.
QQ|Archiver|手機(jī)版|小黑屋| 派博傳思國際 ( 京公網(wǎng)安備110108008328) GMT+8, 2025-10-9 05:45
Copyright © 2001-2015 派博傳思   京公網(wǎng)安備110108008328 版權(quán)所有 All rights reserved
快速回復(fù) 返回頂部 返回列表
浑源县| 嘉黎县| 乃东县| 凤翔县| 西安市| 磐安县| 申扎县| 云龙县| 衡水市| 兴仁县| 阿鲁科尔沁旗| 贵南县| 伊宁市| 通州区| 丰台区| 泰州市| 晋城| 保德县| 习水县| 汤阴县| 萍乡市| 闻喜县| 青河县| 丰城市| 汉源县| 清流县| 乌恰县| 临澧县| 漠河县| 海晏县| 德清县| 贵州省| 区。| 新绛县| 盐城市| 莱芜市| 德江县| 宜宾县| 张家口市| 玛多县| 青海省|