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Titlebook: Epigenetic Advancements in Cancer; Manoj K. Mishra,Kumar S. Bishnupuri Book 2016 Springer International Publishing Switzerland 2016 DNA me

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發(fā)表于 2025-3-21 19:02:10 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Epigenetic Advancements in Cancer
編輯Manoj K. Mishra,Kumar S. Bishnupuri
視頻videohttp://file.papertrans.cn/314/313211/313211.mp4
概述Explores epigenetic landscape that occur in various cancer cells and the role of these changes in cancer initiation and progression.Discusses recent technological advancements that allow epigenetic al
圖書封面Titlebook: Epigenetic Advancements in Cancer;  Manoj K. Mishra,Kumar S. Bishnupuri Book 2016 Springer International Publishing Switzerland 2016 DNA me
描述This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression..?.Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding RNAs expression are involved in a complex network of regulating expression of oncogenes and tumor suppressor genes and constitute an important event of the multistep process of carcinogenesis. Recent advances in the understanding of the epigenetic regulation and detailed information of these epigenetic changes in various cancers provide new avenues of advancements in diagnostics, prognostics, and therapies of this highly fatal disease..
出版日期Book 2016
關鍵詞DNA methylation; Gene-expression control; Histone modifications; RNA expression; Epigenetic regulators; g
版次1
doihttps://doi.org/10.1007/978-3-319-24951-3
isbn_softcover978-3-319-79706-9
isbn_ebook978-3-319-24951-3
copyrightSpringer International Publishing Switzerland 2016
The information of publication is updating

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發(fā)表于 2025-3-21 21:37:19 | 只看該作者
https://doi.org/10.1007/978-3-663-01431-7epigenetic events, the combination of epigenetic patterns obviate the changes. However, most tumors strongly exhibit epigenetic dysfunctions of genes crucial to the cell cycle. The analysis of epigenetic changes, degree of the change and reversal of epigenetic alterations is important to the diagnos
板凳
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https://doi.org/10.1007/978-3-642-47766-9ove, induce epigenetic changes associated with the expression of tumor suppressor genes, such as . and inhibition of tumor promoting genes such as telomerase reverse transcriptase during tumor progression. Therefore, in this chapter, we present considerable evidence that bioactive compounds and thei
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Alte Gesellschaft — Neue Medienonents of the DNA itself, they have the potential to be passed on to offspring. Novel drug therapies are being developed to target particular aberrant epigenetic activity responsible for initiating harmful health effects.
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Historische Improvisation heutely silenced or activated are generally tumor suppressor genes (TP53, CDK2NA, Retinoblastoma) or oncogenes (Wnt, KRAS, BRAF, PIK3CA) respectively that play a crucial role in cell cycle regulation. Furthermore, epigenetic alteration of mismatch repair genes can contribute to cancer through the phenome
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https://doi.org/10.1007/978-3-322-87452-8ing breast cancer. Recent advances in the field implicated that DNA methylation profiles and histone modifications are strongly associated with breast tumor subtypes and patient prognosis. Therefore, understanding contributions of epigenetics to breast cancer biology will lead to better diagnostic a
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發(fā)表于 2025-3-23 04:10:16 | 只看該作者
Dortmunder Beitr?ge zur Sozialforschungneration cancer therapies. Therefore, in this chapter we provide an analysis of novel cancer treatment methods that target epigenetic factors such as Ezh2. We will examine key examples of Ezh2 regulation in prostate cancer as well as novel drug concepts that employ epigenetic targets. This chapter w
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