Titlebook: Engineering and Physical Approaches to Cancer; Ian Y. Wong,Michelle R. Dawson Book 2023 The Editor(s) (if applicable) and The Author(s), u

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Physical Regulations of Cell Interactions and Metabolism in Tumor Microenvironments,sis accounting for over 90% of cancer-associated mortality. Elucidating the process of tumor progression in the primary tumor is important to the understanding of the sequence of events that gives rise to late stage/metastatic cancer. The primary tumor microenvironment (TME) is a dynamic, heterogene

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,Biophysical Regulation of TGFβ Signaling in the Tumor Microenvironment,sis. The tumor microenvironment experiences dynamic changes in composition and mechanical properties, including alignment of matrix components and variations in the stiffness of the stroma, during cancer progression and recent studies have started to elucidate how these changes govern TGFβ signaling

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Engineering Approaches in Ovarian Cancer Cell Culture,n cancer (OC) biopsies have provided crucial information about the heterogeneity of cancer cell assemblies and their various tumor microenvironments (TMs). Translating this information into tumor biology for the discovery of new treatments could be accomplished by the engineering tissue culture mode

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Biophysical Properties and Isolation of Circulating Tumor Cells,the fluid environment, the small fraction of CTCs that are able to resist destruction and elimination have the potential to form metastatic colonies and can therefore be considered metastatic precursors. CTC survival in the circulatory system is dependent on a number of factors including interaction

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