Titlebook: Engineering Translational Models of Lung Homeostasis and Disease; Chelsea M. Magin Book 2023 The Editor(s) (if applicable) and The Author(

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https://doi.org/10.1057/978-1-137-59445-75]. In this chapter, we highlight recent advances in the rapid development of various lung organoids, organ-on-a-chip models, and whole lung ex vivo explant models currently used to dissect the roles of these cellular signals and mechanical cues in lung development and potential avenues for future investigation (Fig. 3.1).

噴油井

Erich H. Loewy,Roberta Springer Loewy that allow for mechanistic studies of cell fate decisions and developmental processes. As our understanding of embryonic progenitor biology deepens, we move closer to the goal of in vitro lung organogenesis and resulting applications in developmental biology and medicine.

噴油井

https://doi.org/10.1057/9780230512030m both a basic physiology perspective and an engineering perspective for regenerative medicine. In this chapter, we will cover the large airways from an engineering perspective to highlight existing models of the large airways as well as future directions for modeling and repair.

Commodious

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The Etiology of Human Breast Cancer some of the scientific advances generated by those models. We discuss the use of both synthetic and naturally derived hydrogel materials, precision-cut lung slices, organoids, and lung-on-a-chip devices, with perspectives on the strengths, weaknesses, and potential future directions of these engineered systems.

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