Titlebook: Endotoxins: Structure, Function and Recognition; Xiaoyuan Wang,Peter J. Quinn Book 2010 Springer Science+Business Media B.V. 2010 Antigen.

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Aufbereitung des Datenmaterials,e end of the reaction. The Factor C, which normally exists as a zymogen, is the primer of this coagulation cascade. In vivo, Factor C is the perfect biosensor, which alerts the horseshoe crab of the presence of a Gram-negative invader. The hemostatic end-point entraps the invader, killing it and lim

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https://doi.org/10.1007/978-3-662-70041-9er hand, this contrasts with acute infection-causing . where overt inflammation contributes to pathology and diarrhoea production, and whose endotoxin is immunologically and endotoxically active. Futhermore, both . and . exhibit molecular mimicry in the saccharide components of their endotoxins whic

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https://doi.org/10.1007/978-3-662-65830-7ign non-peptidic, nontoxic, small-molecule LPS-sequestrants. Our efforts began with defining the central pharmacophore that determined LPS-recognition and -neutralization properties in small molecules, which led to the discovery of a novel lipopolyamine lead, DS-96. DS-96 is an effective LPS-neutral

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Purification and Characterization of Lipopolysaccharideslecule. They can cause severe diseases like sepsis and therefore known as endotoxins. Lipopolysaccharide consists of lipid A, core oligosaccharide and O-antigen repeats. Lipid A is responsible for the major bioactivity of endotoxin. Because of their specific structure and amphipathic property, purif

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The Diversity of the Core Oligosaccharide in Lipopolysaccharidesontribute to the cellular rigidity by increasing the strength of cell wall and mediating contacts with the external environment that can induce structural changes to allow life in different conditions. Furthermore, the low permeability of the outer membrane acts as a barrier to protect bacteria from