Titlebook: Endotoxin; Herman Friedman,T. W. Klein,Alois Nowotny Book 1990 The Editor(s) (if applicable) and The Author(s), under exclusive license to

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Methodologie, Vorgehensweise, Grenzen,rm our hypothesis concerninglipid A epitopes.In the presentstudy, therefore, we examined the in vitro antigenic reactivity of synthetic lipid A analogs and bacterial lipid A with monoclonal and conventional antibodies against the lipid A of . F515, . J5 and . JCM 2788, as well as . R595 by the ELISA

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T?tigkeit der OperationsschwesterVukajlovich and Morrison prepared homogeneous monomeric components of . 055:B5 LPS (17). One of these fractions, which was protein-free, enriched in lipid A and contained a trace of 0-antigen, induced a significant but limited amount of .H-thymidine incorporation by C3H/HeJ splenic lymphocytes as co

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Structural Requirements of Lipid a for Endotoxicity and Other Biological Activities—An Overviewn 1954 Westphal and Lüderitz proposed that the lipid moiety of LPS is responsible for most of endotoxicities, and designated it as lipid A (Fig 1) (60). However, this extremely important discovery was neither adequately nor unanimously accepted by endotoxin investigators at that time. One of the mai