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Titlebook: Endothelin and Its Inhibitors; Timothy D. Warner Book 2001 Springer-Verlag Berlin Heidelberg 2001 Circulation.Endothelin.Glatte Muskulatur

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發(fā)表于 2025-3-21 20:02:20 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Endothelin and Its Inhibitors
編輯Timothy D. Warner
視頻videohttp://file.papertrans.cn/310/309945/309945.mp4
概述Since its characterisation in 1988, endothelin research has moved very rapidly..A little over 10 years of research have produced the most dramatic developments..Recent publications have addressed spec
叢書名稱Handbook of Experimental Pharmacology
圖書封面Titlebook: Endothelin and Its Inhibitors; Timothy D. Warner Book 2001 Springer-Verlag Berlin Heidelberg 2001 Circulation.Endothelin.Glatte Muskulatur
描述Recent publications have addressed specific aspects of the endothelins, such as their roles in disease or the importance of endothelin receptors. However, in this book the entire field of endothelins is covered. This includes the pathways of endothelin production and their regulation, the local and systemic actions of endothelins, receptors for the endothelins and the signalling pathways employed, and the involvement of endothelins in a range of diseases. Attention is also paid to the development through chemistry, pharmacology and toxicology of endothelin antagonists and endothelin-converting enzyme inhibitors, with mention of all the important members of these drug classes. This leads to well-rounded discussions of the potential therapeutic benefit of endothelin inhibitors.
出版日期Book 2001
關(guān)鍵詞Circulation; Endothelin; Glatte Muskulatur; Kreislauf; Peptide; Peptides; Smooth Muscle; endothelium; tissue
版次1
doihttps://doi.org/10.1007/978-3-642-56899-2
isbn_softcover978-3-642-63237-2
isbn_ebook978-3-642-56899-2Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 2001
The information of publication is updating

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Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/e/image/309945.jpg
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發(fā)表于 2025-3-22 01:41:34 | 只看該作者
https://doi.org/10.1007/978-3-642-56899-2Circulation; Endothelin; Glatte Muskulatur; Kreislauf; Peptide; Peptides; Smooth Muscle; endothelium; tissue
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Endothelins Within the Liver and the Gastrointestinal System,(GI) smooth muscle preparations, and the relationships of these responses to the expression (mRNA), synthesis, production, and degradation of the endothelins and the distribution of ET receptors. Attention is also given to the possible physiological and pathophysiological roles of ETs in the gastrointestinal tract and related organs.
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Endothelin and Its Inhibitors978-3-642-56899-2Series ISSN 0171-2004 Series E-ISSN 1865-0325
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發(fā)表于 2025-3-22 23:53:48 | 只看該作者
https://doi.org/10.1007/978-3-642-99265-0overy of endothelium-derived relaxing factor (EDRF) ((Furchgott and Zawadzki 1980). EDRF was later proved to be a simple substance, nitric oxide (Palmer et al. 1987). At that time, numerous studies provided evidence of a role for arachidonic acid and its metabolites in the endothelium-dependent resp
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Erich Schild,Rainer Oswald,Reinhard Lamersmino acid residues) which undergo selective proteolysis to yield the biologically inactive intermediates called big endothelins (Bloch et al. 1989a,b; Ohkubo et al. 1990; Yanagisawa et al. 1988). The human ET-1 gene encodes a 212 amino acid precursor, preproendothelin-1 (Bloch et al. 1989b). Removal
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