Titlebook: Endothelial Function in Hypertension; David Webb,Patrick Vallance Conference proceedings 1997 Springer-Verlag Berlin Heidelberg 1997 ather

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https://doi.org/10.1007/978-3-658-33062-0cell adhesion molecule-1 and monocyte chemotactic protein-1..Enhancement of endogenous NO activity may be a new therapeutic strategy for preventing the progression of atherosclerotic vascular disease, restenosis, and thrombosis.

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Endothelial Function in Hypertension: Role of Nitric Oxide,r NO synthase. In human hypertension, pharmacological experiments reveal an impaired NO dilator mechanism. In pulmonary hypertension, the use of NO gas inhalation has been proposed as a future therapy for this condition. This chapter reviews the evidence, concentrating on the evidence from animal mo

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Endothelial Factors and Myocardial Function,ous to endothelium-dependent regulation of vascular tone. In bioassay studies using cultured ventricular endocardial endothelial cells and isolated papillary muscle preparations, Shah and colleagues (Smith et al. 1991) demonstrated that these effects were mediated by the release of diffusible factor

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Vascular Biology of the Endothelin System,paired cysteine amino acid residues and all of which are formed through the same processing pathway (Fig. 2). Their respective precursor peptides share high sequence homology but are encoded by distinct genes [7]. It is also clear [8] that the endothelin isopeptides share remarkable structural simil

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Endothelin in Hypertension: A Role in Vascular Hypertrophy?,vascular hypertrophy in these experimental models of hypertension, whereas it has no effect on SHR. The latter do not overexpress endothelin in blood vessels. In some severe hypertensive patients there is overexpression of endothelin-1 in endothelium of small arteries. These results suggest that end

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https://doi.org/10.1007/978-3-322-95122-9r NO synthase. In human hypertension, pharmacological experiments reveal an impaired NO dilator mechanism. In pulmonary hypertension, the use of NO gas inhalation has been proposed as a future therapy for this condition. This chapter reviews the evidence, concentrating on the evidence from animal mo

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