Titlebook: Endocytosis and Signaling; Christophe Lamaze,Ian Prior Book 2018 Springer International Publishing AG, part of Springer Nature 2018 cell s

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Endosomal Trafficking During Mitosis and Notch-Dependent Asymmetric Division, and specification which play a central role in development and physiology. In this chapter, we cover a number of significant works on endosomal trafficking evincing the importance of endocytosis in Notch-mediated cell fate specification during development.

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GTPases Rac1 and Ras Signaling from Endosomes,eous complex structures that transport, amplify, sustain, and/or sort signaling molecules. Over the years, it has become evident that early, late, and recycling endosomes represent an interconnected vesicular-tubular network able to form signaling platforms that dynamically and efficiently translate

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ESCRT and Membrane Protein Ubiquitination,or Transport (ESCRT). This molecular machinery is composed of five distinct multi-subunit complexes. On the surface of endosomes, ESCRT-0, -I and -II bind to ubiquitinated membrane proteins, while ESCRT-III and Vps4 bud intraluminal vesicles (ILVs) into the lumen of the endosomes. By working togethe

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TEN

Interplay of Endocytosis and Growth Factor Receptor Signalling,ferent cellular contexts and with different cellular outcomes. This begs the question as to how cells in a particular developmental, spatial and temporal context, or in adult tissue, interpret signalling by growth factor receptors in order to deliver qualitatively different signalling outputs. One m

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Role of the Endocytosis of Caveolae in Intracellular Signaling and Metabolism,processes in the plasma membrane—ranging from the organization of signalling complexes to the mechanical adaptation to changes in PM tension. However, since their initial descriptions, these structures have additionally been found tightly linked to internalization processes, mechanoadaptation, to th

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