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Titlebook: Endocrine Therapy and Growth Regulation of Breast Cancer; Urs Eppenberger,Aron Goldhirsch (Vice-Primario) Conference proceedings 1989 Spri

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發(fā)表于 2025-3-21 18:09:40 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Endocrine Therapy and Growth Regulation of Breast Cancer
編輯Urs Eppenberger,Aron Goldhirsch (Vice-Primario)
視頻videohttp://file.papertrans.cn/310/309734/309734.mp4
叢書名稱Recent Results in Cancer Research
圖書封面Titlebook: Endocrine Therapy and Growth Regulation of Breast Cancer;  Urs Eppenberger,Aron Goldhirsch (Vice-Primario) Conference proceedings 1989 Spri
描述Key questions involved in the treatment of disseminated breast cancer are discussed in this well-presented overview. It is the result of an initiative taken by the Swiss Group for Clinical Cancer Research to reveal the most recent developments in experimental and clinical research. The topics discussed include: the comparison of in vitro cultures of epithelial cells with breast cancer cells, the effect of steroids and their antagonists, the involvement of suppressor genes in tumour progression, the modulation of transforming growth factors by estrogen, and prognostic factors such as cERB-2 and EGF-R in breast cancer.
出版日期Conference proceedings 1989
關(guān)鍵詞breast cancer; cancer; cancer research; carcinoma; growth; growth factor; protein; regulation; steroid; stero
版次1
doihttps://doi.org/10.1007/978-3-642-83638-1
isbn_softcover978-3-642-83640-4
isbn_ebook978-3-642-83638-1Series ISSN 0080-0015 Series E-ISSN 2197-6767
issn_series 0080-0015
copyrightSpringer-Verlag Berlin Heidelberg 1989
The information of publication is updating

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發(fā)表于 2025-3-21 20:14:00 | 只看該作者
In Vitro Cultures of Epithelial Cells from Healthy Breast Tissues and Cells from Breast Carcinomas,cell lines (Lippman et al. 1986; Salomon et al. 1986). During the last few years, techniques have been described which allow the growth directly from patients’ tissue of normal human breast epithelial cells (Stampfer et al. 1980; Stampfer 1982; Biran et al. 1983; Taylor-Papadimitriou et al. 1980; Ha
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Ribosomal Protein S6 Kinase and PKC in Human Mammary Tumor Cells,nat 1983; Howat et al. 1985), but it is unclear wheter E. acts directly or indirectly on the proliferation of target cells (Soto and Sonnenschein 1987; Dickson and Lippman 1987; King 1985). At present, there is increasing evidence that polypeptide growth factors (GF) also regulate the growth of huma
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Epidermal Growth Factor Receptor in Human Breast Cancer,ntification has been a radioligand assay in which .I-labelled EGF is incubated with membranes prepared from both primary and metastatic tumours, both alone and in the presence of a large excess of unlabelled EGF, the difference in binding under these two conditions representing specific binding (for
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發(fā)表于 2025-3-23 00:56:27 | 只看該作者
The Transformation-Suppressive Function Is Lost in Tumorgenic Cells and Is Restored upon Transfer oeen analyzed by DNA transfection experiments and dominantly acting cellular oncogenes have been identified. The introduction of single activated oncogenes into immortalized cell lines such as mouse NIH/3T3 cells is sufficient for tumorigenic transformation. The requirements for malignant transformat
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發(fā)表于 2025-3-23 04:09:16 | 只看該作者
Elizabeth’s Presence in the Jacobean Masquegrowth regulation of human breast epithelium cells. Such a transcriptional control is achieved through the interaction of transacting factors with the respective promoter elements located on the DNA. The steroid receptor proteins belong to such a family of regulatory proteins. The ability of these p
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發(fā)表于 2025-3-23 09:19:13 | 只看該作者
https://doi.org/10.1007/978-1-4613-8566-0 (GF-R). Such GF-Rs are likely to represent important growth-regulatory elements in the estrogen-induced autocrine or paracrine growth mechanisms of human breast cancer (Fitzpatrick et al. 1984; Macias et al. 1986; Sainsbury et al. 1985; Wyss et al. 1987; Sainsbury et al. 1987; Furlanetto and DiCarl
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