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Titlebook: Endocrine Therapies in Breast and Prostate Cancer; C. Kent Osborne Book 1988 Kluwer Academic Publishers, Boston 1988 carcinoma.cell.clinic

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發(fā)表于 2025-3-21 19:56:30 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Endocrine Therapies in Breast and Prostate Cancer
編輯C. Kent Osborne
視頻videohttp://file.papertrans.cn/310/309733/309733.mp4
叢書名稱Cancer Treatment and Research
圖書封面Titlebook: Endocrine Therapies in Breast and Prostate Cancer;  C. Kent Osborne Book 1988 Kluwer Academic Publishers, Boston 1988 carcinoma.cell.clinic
描述It has been recognized for many years that cancers originating in the breast and prostate gland are frequently ‘endocrine-dependent. ‘ Traditional thera- pies included surgical endocrine ablative procedures or pharmacologic hor- mone administration, both designed to antagonize the stimulatory effects of sex steroid hormones. In the past decade, several new treatment strategies for these tumors have emerged from basic studies in reproductive biology and mechanisms of action of steroid hormones. In some instances, these new treatments have elimin- ated or reduced the need for major surgical ablative procedures or for toxic hormone therapy. The clinical role for other new treatments has not yet been clearly defined, although exciting preliminary data from recent clinical trials are now available. Thus, an objective review of the current status of these new therapeutic approaches is of interest. In this volume we have attempted to provide an in-depth review of both basic and clinical research involving several new treatment strategies for breast and prostate cancer. The first three chapters summarize preclinical and clinical studies of the luteinizing hormone-releasing hormone analogue
出版日期Book 1988
關鍵詞carcinoma; cell; clinical trial; hormones; prostate cancer
版次1
doihttps://doi.org/10.1007/978-1-4613-1731-9
isbn_softcover978-1-4612-8974-6
isbn_ebook978-1-4613-1731-9Series ISSN 0927-3042 Series E-ISSN 2509-8497
issn_series 0927-3042
copyrightKluwer Academic Publishers, Boston 1988
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Pungent Silence: Encounters with Onion,ave consisted of surgical removal of endocrine glands such as ovaries, adrenals, and pituitary or administration of pharmacologic amounts of hormones such as estrogens, androgens, and progestational agents [1]. Although the hormone dependency of human breast cancer has been recognized since the end
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Why We Cannot Think about Nonexistents,w cases will be diagnosed in 1988; most will present with metastatic disease. The median survival for patients with newly diagnosed, metastatic prostate cancer is approximately three years. Since the pioneering work of Huggins and Hodges in the 1940s, which demonstrated the androgen-dependence of pr
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https://doi.org/10.1057/9780230510319d of human breast carcinomas are ‘hormone-dependent’ and respond to various endocrine manipulations, which are usually designed to block the stimulatory effects of estrogen on tumor growth. Although the mechanisms by which additive hormone therapies, such as pharmacologic estrogens or progestins, in
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Representations of Childhood Deathed that in 1987 there were 96,000 newly diagnosed cases and 27,000 deaths from prostatic cancer in the United States [1] Approximately 50% of men with prostatic cancer have advanced disease at the time of initial presentation. The realistic objective of treatment in these patients is palliation rath
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https://doi.org/10.1007/978-1-4613-1731-9carcinoma; cell; clinical trial; hormones; prostate cancer
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