Titlebook: Emerging Anti-Aging Strategies; Syed Ibrahim Rizvi Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license to S

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Book 2023eutic intervention. Finally, the book reviews the ethical dimension of anti-aging intervention strategies. This book is immensely useful to scientists and researchers from various disciplines in the life sciences.

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Genetics and Epigenetics of Aging and Age-Associated Diseases,ications, and chromatin remodeling among other events that define how organismal function pursues. Effective research within the area towards the identification of specific genetic and epigenetic targets can deliver senolytic compounds and other anti-aging strategies thus promoting healthy aging and

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Autophagy as a Promising Therapeutic Target in Age-Associated Neurodegenerative Disorders,ntions in AD and PD. Administration of caloric restriction mimetics like spermidine, rapamycin, metformin, and fisetin have shown to improve cognitive functioning in AD and PD through autophagy activation.

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Glycolytic Inhibitors as Caloric Restriction Mimetics (CRM),lism, whereas downstream CRMs regulate intracellular signaling. Metformin (an anti-diabetic medicine that activates AMPK), Rapamycin (an immunosuppressive drug that inhibits mTOR), Resveratrol (a polyphenol that activates Sirtuin), and other downstream drugs are just a few examples. Glycolytic inhib

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Anti-aging and Rejuvenation Based on Stem Cell Therapy,of stem cells. This is why there is a decrease in the potential for regeneration. Aging involves the loss of optimal functions of the organism over time. Cell therapy could potentially be one of the most promising therapies to control aging due to the fact that single stem cell transplantation can r

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Anti-inflammatory-Dependent Anti-aging Strategies,ng by activating the body’s compensatory mechanism. Aging is strongly affected by metabolism. Research on drugs such as polyphenolic compounds, statins, and aspirin will increasingly continue, as they can delay the aging process, prolong lifespan, and reduce age-related degeneration and associated m

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Spermidine, an Autophagy Inducer, as a Therapeutic Antiaging Strategy,ar senescence. Further, recent research highlight the potential of spermidine to delay the aging process. Still, the antiaging mechanisms of spermidine remain unknown. This chapter aims to explore the role of spermidine in the brain and to summarize the epigenetic effects of spermidine linked with a