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Titlebook: Effects of Mineral Dusts on Cells; Brooke T. Mossman,Raymond O. Bégin Conference proceedings 1989 Springer-Verlag Berlin Heidelberg 1989 A

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書目名稱Effects of Mineral Dusts on Cells
編輯Brooke T. Mossman,Raymond O. Bégin
視頻videohttp://file.papertrans.cn/303/302866/302866.mp4
叢書名稱Nato ASI Subseries H:
圖書封面Titlebook: Effects of Mineral Dusts on Cells;  Brooke T. Mossman,Raymond O. Bégin Conference proceedings 1989 Springer-Verlag Berlin Heidelberg 1989 A
描述The Fourth International Workshop on "In Vitro Effects of Mineral Dusts on Cells" was held on September 20 - 23, 1988 in Auberge Estrimont, Orford, Quebec, Canada. The emphasis of the N. A. T. O. Advanced Research Workshop was the use of cell and organ culture and lavage cell populations obtained from man and laboratory animals to elucidate cellular and molecular events occur- ring after their interaction with fibrous and nonfibrous particulates, including metal compounds. In seven sessions, an international representation of scientists from 17 countries (Austria, Belgium, Canada, France, Federal Republic of Germany, India, Japan, Netherlands, Norway, Poland, Portugal, Union of South Africa, Sweden, Switzerland, United Kingdom, United States of America, and Yugoslavia) presented recent research findings in the following areas: Epithelial cell injury and proliferation by minerals. Physico-chemical properties of minerals in relation to their biologic effects. Mechanisms of dust-induced pneumoconioses. Clinical and experimental studies. Mechanisms of cytotoxicity, mutagenicity and carcinogenicity. Oxidants, cytotoxicity and disease. Mechanisms of mineral-induced inflammation. Mechanis
出版日期Conference proceedings 1989
關鍵詞Atmen; biology; cell; inflammation; molecular biology; mutagenicity; oncogenes; ecotoxicology
版次1
doihttps://doi.org/10.1007/978-3-642-74203-3
isbn_softcover978-3-642-74205-7
isbn_ebook978-3-642-74203-3Series ISSN 1010-8793
issn_series 1010-8793
copyrightSpringer-Verlag Berlin Heidelberg 1989
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Bronchoalveolar Lavage Cells in Occupational Exposure to Mineral Fibersosure are among the most extensively studied, but several problems remain open. In our institution, workers occupationally exposed to mineral fibers represent approximately one third of over 300 subjects investigated by BAL since 1983.
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Mutagenicity of Asbestos and Erionite in a , Tester Strain of TA102ange (SCE) (Livingston et al. 1980; Babu et al. 1981) asbestos has produced negative results in most of the short-term genotoxicity tests for the detection of genetic effects. As a consequence, Hesterberg and Barret (1985) have postulated an epigenetic mechanism of asbestos carcinogenicity.
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Conference proceedings 1989ebec, Canada. The emphasis of the N. A. T. O. Advanced Research Workshop was the use of cell and organ culture and lavage cell populations obtained from man and laboratory animals to elucidate cellular and molecular events occur- ring after their interaction with fibrous and nonfibrous particulates,
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https://doi.org/10.1007/978-1-4419-9890-3 Histopathologic studies in animals indicate that the effect of increased dust retention is increased penetration of dust into the walls of small airways. Again this is true for both inert and toxic dusts (McFadden et al 1986b; Gilks et al 1988).
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Data Monitoring Committees (DMCs)for production, consumption, and application data). Concern about the potential health hazard of these minerals has arisen due to their fibrous nature and extensive application as asbestos substitutes (Bignon .., 1980).
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