Titlebook: Drugs of Abuse, Immunomodulation, and Aids; Herman Friedman,John J. Madden,Thomas W. Klein Book 1998 The Editor(s) (if applicable) and The

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Immunomodulation of Macrophage Functions by Opioids,e physical dependence. Structurally, opioids are phenanthrene derivatives (morphine), phenypiperidine derivatives (fentanyl), diphenylheptane derivatives (methadone),. and pep tide-related compounds (en- dorphin, enkephalin, and dynorphin).. Opioids exert their major pharmacologic effect on the cent

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,The Expression of Interleukin-1β Converting Enzyme (ICE) in Rat is Decreased Following Chronic Expoe most important of these cytokines is interleukin-1 β (IL-lβ), which has been shown to play a key role in the immune response by promoting the proliferation of T-cells, inducing the secretion of IL-2, and stimulating the function of B-cells and natural killer cells. In addition, IL-lβ is important

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Morphine Alters the Immune Response to Influenza Virus Infection in Lewis Rats, population has decreased mitogenic responsiveness of blood lymphocytes to lipopolysaccharide, poke- weed mitogen, and concanavalin-A, suggesting an impairment of cellular immunity (1). Subsequent studies have shown that chronic heroin users also exhibit diminished T-cell E-rosetting (2), reductions

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