Titlebook: Drugs of Abuse, Immunity, and Immunodeficiency; Herman Friedman,Steven Specter,Thomas W. Klein Book 1991 The Editor(s) (if applicable) and

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Pascale Carayon,Abigail R. Wooldridge early as the mid 1970’s. (Reviewed in 1). However, these studies yielded conflicting data necessitating further investigations. Recent studies by Friedman and co-workers confirmed the immune suppressive effects of THC in mice using . and . experimental models (2–5). Klein et al. (6) reported depres

Monolithic

Modeling Engineering Student Success Needsympho-proliferative response to alloantigens in chronic marijuana smokers (1). Since then, numerous investigators have pursued studies involving the effects of various cannabinoids from marijuana, including the major psychoactive component, ?.-tetrahydrocannabinol (THC), found in the blood of mariju

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Saba A. Al-Sayouri,Sarah S. Lamey roles in immunomodulation and host defense (1,2), and exert also metabolic effects (3,4). Therefore, a change in cytokine secretion caused by drugs of abuse could have an impact on immunological systems and metabolism. Delta-9-tetrahydrocannabinol (THC), the major psychoactive component of mariju

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Saba A. Al-Sayouri,Sarah S. Lamnd in experimental animals. The drug decreases host resistance to viruses (1–3) and bacteria (1), alters cellular morphology and function (4–10), and inhibits RNA, DNA, and protein synthesis (11–13). These effects on macromolecular synthesis suggest that THC may elicit its immunosuppressive effects

achlorhydria

Nedret Billor,Asuman S. Turkmene is not entirely understood, however, it has been suggested that it may have a role in macrophage function in the immune system. For some time we have utilized mouse peritoneal cells as a model system in which to study cannabinoid effects on the release of arachidonic acid and its subsequent conver

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Modeling Engineering Student Success Needs parameters of the immune response. These parameters include lymphocyte proliferation, macrophage spreading, and antibody production (1–3). Studies have suggested that THC has different magnitudes of effect depending on the lymphoid organ analyzed (2) as well as the age of the animal (4). Different

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