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Titlebook: Drugs between Research and Regulations; Proceedings of the 5 C. Steichele (Medizinischer Direktor),U. Abshagen Conference proceedings 1985

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41#
發(fā)表于 2025-3-28 16:18:56 | 只看該作者
42#
發(fā)表于 2025-3-28 22:25:57 | 只看該作者
Chronic toxicity tests, current problems and possible solutionsmple hyperplasia to benign and malignant tumors, metabolic disturbances such as fatty infiltration, glycogenosis and phospholipidosis, organ degenerations, e.g. atrophy, swelling and necrosis, and reactive responses such as inflammation, fibrosis and cirrhosis.
43#
發(fā)表于 2025-3-29 02:35:38 | 只看該作者
What good are clinical trials?d each one involves patient care, the time of physicians and staff. Many require large amounts of money and other resources and therefore to make a judgement of how good they are will always be a question of balance, not only between benefit and risk but also between value in its widest sense and the resources expended.
44#
發(fā)表于 2025-3-29 05:34:27 | 只看該作者
45#
發(fā)表于 2025-3-29 10:30:51 | 只看該作者
Alternatives to chronic toxicity studiesor different sectors of our chemical world, for example, OECD regulations for testing of chemicals, EEC and FDA regulations for testing pharmaceutical substances. The requirements differ in regard to the number and selection of species, number of animals per dose group and experiment, modes of application and duration of experiment.
46#
發(fā)表于 2025-3-29 12:20:37 | 只看該作者
47#
發(fā)表于 2025-3-29 18:08:28 | 只看該作者
48#
發(fā)表于 2025-3-29 22:52:16 | 只看該作者
49#
發(fā)表于 2025-3-30 02:52:26 | 只看該作者
50#
發(fā)表于 2025-3-30 04:07:21 | 只看該作者
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