Titlebook: Drugs Targeting B-Cells in Autoimmune Diseases; Xavier Bosch,Manuel Ramos-Casals,Munther A Khamash Book 2014 Springer Basel 2014 Cryoglobu

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B-Cell Targeted Therapies in Cryoglobulinemia,ntext of these three concomitant biologic events linked one to each other, i.e., chronic infection, autoimmunity, and B-cell lymphoproliferation. Since rituximab is used for B-cell depletion in CV, this drug will be herein discussed.

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Book 2014 arthritis, systemic lupus erythematosus, Sj?gren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell

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Book 2014ed evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases..

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Arne L. Kalleberg,Kevin T. Leichtd trials. Belimumab has been licensed for use in SLE in 2011 by the FDA and European Medicines Agency. Forthcoming years will show the real value of B-cell targeted therapies, including the off-label use of rituximab and especially the licensed use of belimumab, as part of the standard of care in patients with SLE.

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