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Titlebook: Drugs Affecting Lipid Metabolism; Rodolfo Paoletti (Dean),David Kritchevsky (Associa Conference proceedings 1987 Springer-Verlag Berlin He

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書(shū)目名稱Drugs Affecting Lipid Metabolism
編輯Rodolfo Paoletti (Dean),David Kritchevsky (Associa
視頻videohttp://file.papertrans.cn/284/283179/283179.mp4
叢書(shū)名稱Proceedings in Life Sciences
圖書(shū)封面Titlebook: Drugs Affecting Lipid Metabolism;  Rodolfo Paoletti (Dean),David Kritchevsky (Associa Conference proceedings 1987 Springer-Verlag Berlin He
描述The recent symposium and the appearance of this new book on Drugs Affecting Lipid Metabolism take place at a very unusual time for the development of this area. After the publication and wide acceptance of the results of the cholestyramine study by the Lipid Clinics in the USA, showing for the first time a direct association between drug induced reduction of plasma levels of total and LDL cholesterol and coronary heart disease in a high risk population, an unparalleled interest in drugs and other procedures able to control plasma cholesterol levels has been activated. Two other significant events occurred during 1986 and 1987: the availability of compact instruments for the immediate determination of total cholesterol in plasma or total blood and the developments of new agents such as the inhibitors of HMG-CoA (hydroxymethyl- glutaryl CoA) reductase and ACAT inhibitors, with potentially great effect on plasma lipid levels after oral administration. These new advances, together with the combined efforts of cell biologists and lipoprotein chemists, have set the pace for an exciting period of research and clinical applications of diets and drugs af- fecting lipids. This volume, which
出版日期Conference proceedings 1987
關(guān)鍵詞Lipid; Lipoprotein; development; drug; lipide; metabolism; protein; research
版次1
doihttps://doi.org/10.1007/978-3-642-71702-4
isbn_softcover978-3-642-71704-8
isbn_ebook978-3-642-71702-4Series ISSN 0172-6625
issn_series 0172-6625
copyrightSpringer-Verlag Berlin Heidelberg 1987
The information of publication is updating

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Keith Kroll,James Bassingthwaighteever, studies of new agents have taught us important lessons regarding normal lipid and lipoprotein metabolism. In this presentation I wish to take up three “case histories” in the latter category: (1) bile acid sequestrants; (2) inhibitors of cholesterol biosynthesis, particularly inhibitors of HMG CoA reductase; (3) probucol.
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Understanding Measures of Landscape Patternrowth. Specifically, in tissues such as the kidney, cell replication is very slow and such tissues have low rates of cholesterol synthesis. By contrast, baby brain and intestine replicate at rapid rates and have active cholesterol synthesis. As we showed some years ago, the very rapid cell growth of
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A Spatial View of Population Dynamicsolesterol 7α-hy-droxylase, which catalyzes the introduction of the hydroxyl group in the 7α-position of the cholesterol molecule, is a mixed-function oxidase, cytochrome P 450-dependent and is located in the smooth endoplasmic reticulum of the liver cell (Myant and Mitropoulos 1977).
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Frames and Riesz bases: a short surveyn of the EHC can be achieved in several ways, but the usual means is by use of resins (sequestrants) that bind bile acids in the intestine and prevent their reabsorption. The bile acid sequestrants most commonly used are cholestyramine and colestipol. Cholestyramine was the drug used in the Lipid Re
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Luis Guarracino,Juan Enrique Santospoprotein AI gene which was not present in normolipidaemic individuas (Rees et al. 1983). This RFLP arises because of the existence of a polymorphic nucleotide in the 3’ non-coding region of the linked apo-CIII gene that creates an additional cleavage site for the restriction enzyme SacI (Shoulders
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